Specimen and Data Study for Ovarian Cancer Early Detection and Prevention
RATIONALE: To improve strategies for detection and prevention of early-stage disease. PURPOSE: This research study is collecting specimens and data to develop better methods for early detection and prevention of ovarian cancer among the high risk population and those who have the disease.
Conditions studied
Cervical Cancer, Endometrial Cancer, Fallopian Tube Cancer, Hereditary Breast/Ovarian Cancer (brca1, brca2), Ovarian Cancer, Sarcoma, Uterine Leiomyomata, Vaginal Cancer, Vulvar Cancer
About this study
RATIONALE: To improve strategies for detection and prevention of early-stage disease. PURPOSE: This research study is collecting specimens and data to develop better methods for early detection and prevention of ovarian cancer among the high risk population and those who have the disease.
Interventions
- Other: Ca-125 — Subject's blood collected at their follow-up blood draw will be assessed for biomarkers that could lead to a panel for detecting early stage ovarian cancer.
- Other: screening questionnaire administration — Questionnaires designed to assess quality of life for women at increased risk of ovarian cancer will be administered to the subjects. Clinical data will also be collected.
- Procedure: Surgery — Subjects will be assessed for high risk factors.
Primary outcomes
- The development of ultrasound and serum tumor markers for the detection and management of ovarian cancer and other (1 year)
Eligibility information
Study locations
- Robert H. Lurie Comprehensive Cancer Center at Northwestern University, Chicago, Illinois 60611-3013 United States
Source: ClinicalTrials.gov. Record last refreshed by Varda Clinical: 2026-09-27.