Clinical trials / NCT00286637
Recruiting

Novel Glaucoma Diagnostics

The purpose of this research is to evaluate novel technologies for the assessment of ocular structure and function, including the scanning device called Optical Coherence Tomography (OCT). We will test the OCT and other devices in their ability to image diseases of the eye and also compare the measurements made with OCT to those of other imaging and visual field devices approved by the Food and Drug Administration (FDA). OCT may be useful for the early diagnosis and monitoring of a variety of types of eye diseases

ClinicalTrials.gov IDNCT00286637
PhaseNot Applicable
Enrollment5000
SponsorWills Eye
Age18 Years
SexALL
I'm interested View official listing

Conditions studied

Glaucoma, Macular Disease

About this study

The purpose of this research is to evaluate novel technologies for the assessment of ocular structure and function, including the scanning device called Optical Coherence Tomography (OCT). We will test the OCT and other devices in their ability to image diseases of the eye and also compare the measurements made with OCT to those of other imaging and visual field devices approved by the Food and Drug Administration (FDA). OCT may be useful for the early diagnosis and monitoring of a variety of types of eye diseases

Primary outcomes

Eligibility information

Inclusion Criteria: * Ability to provide informed consent and to understand the study procedures * Healthy volunteers * Age related macular degeneration (AMD), diabetic retinopathy, central serous chorioretinopathy, and/or glaucoma or glaucoma suspects * (AD Sub-Study ONLY): Subjects diagnosed with AD or MCI. Exclusion Criteria: * Any medical treatment (e.g., chronic corticosteroid, hydroxychloroquine, chloroquine, thioridazine, canthaxanthine) or conditions that affect VF (e.g., stroke) and retinal thickness other than glaucoma. * Strabismus, nystagmus, or any condition that prevents fixation. * Presence of any media opacities that hinders clinical view of the fundus, and any intraocular non-glaucomatous abnormality * History of ocular trauma or intraocular surgery other than uncomplicated glaucoma interventions or cataract extraction at least 3 months previous to participating in the study.

Study locations

Before you participate: Varda Clinical is an independent discovery tool, not the study sponsor or a medical provider. Eligibility can only be determined by the official study team. Discuss potential risks and benefits with a qualified healthcare professional.

Source: ClinicalTrials.gov. Record last refreshed by Varda Clinical: 2026-09-27.