Recruiting

Biospecimen and Medical Data Collection and Tumor Biopsy in Creating Research Tissue Registry in Patients With Inflammatory or Invasive Breast Cancer

This trial studies the biospecimen and medical data collection in creating a research tissue registry in patients with inflammatory or invasive breast cancer. Collecting medical data and storing samples of blood, tissue, and stool from patients with inflammatory breast cancer to study in the laboratory may help doctors find better ways to treat and study inflammatory breast cancer in the future.

ClinicalTrials.gov IDNCT00477100

PhaseNot Applicable

Enrollment1200

SponsorM.D. Anderson Cancer Center

Age18 Years

SexALL

I'm interested View official listing

Conditions studied

Inflammatory Breast Carcinoma, Invasive Breast Carcinoma, Second Primary Malignant Neoplasm

About this study

Interventions

Procedure: Biospecimen Collection — Undergo collection of blood, tissue, and stool
Other: Interview — Participate in interview
Other: Medical Chart Review — Undergo collection of medical data
Other: Questionnaire Administration — Ancillary Studies

Primary outcomes

Data, serum, tissue, peripheral blood mononuclear cells, and plasma sample collection (Up to 2 years)

Eligibility information

Inclusion Criteria: * Patients with clinical diagnosis of primary inflammatory breast cancer (IBC), second primary IBC, or highly suspicious for IBC (MD Anderson patients only). * Histological diagnosis of invasive breast cancer, or highly suspicious for IBC (MD Anderson patients only) but pending breast cancer diagnosis. * Be either newly diagnosed, or highly suspicious for IBC (MD Anderson patients only) \[Cohort I\] or have paraffin blocks or up to 20 unstained slides of each representative block(s) from the time of initial diagnosis of IBC(i.e. core biopsy and punch biopsy) and/or from mastectomy (Cohort II-MD Anderson patients only) * Age \> 18 years * Able to provide informed consent Exclusion Criteria:

Study locations

Banner - MD Anderson Cancer Center, Gilbert, Arizona 85234 United States
Scripps - MD Anderson Cancer Center, La Jolla, California 92037 United States
Banner - MD Anderson Cancer Center - Northern Colorado, Greeley, Colorado 80631 United States
Baptist - MD Anderson Cancer Center, Jacksonville, Florida 32207 United States
Covenant Medical Center, Saginaw, Michigan 48604 United States
M D Anderson Cancer Center, Houston, Texas 77030 United States
MD Anderson in Katy, Houston, Texas 77094 United States
MD Anderson League City, Nassau Bay, Texas 77058 United States
MD Anderson in Sugar Land, Sugar Land, Texas 77478 United States
MD Anderson in The Woodlands, The Woodlands, Texas 77384 United States

Before you participate: Varda Clinical is an independent discovery tool, not the study sponsor or a medical provider. Eligibility can only be determined by the official study team. Discuss potential risks and benefits with a qualified healthcare professional.

Source: ClinicalTrials.gov. Record last refreshed by Varda Clinical: 2026-09-27.