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Physical Activity Program for Reducing Blood Pressure in Sleep Apnea Patients With Resistant Hypertension

Investigators hypothesize that CPAP treatment for suppressing OSAS in combination with a physical activity program will optimize 24-hour blood pressure control in patients with OSA-related resistant hypertension.

ClinicalTrials.gov IDNCT02057783

PhaseNA

Enrollment100

SponsorAGIR à Dom

Age18 Years

SexALL

I'm interested View official listing

Conditions studied

Hypertension, Resistant to Conventional Therapy, Sleep Apnea

About this study

Interventions

Other: Physical activity — Physical activity will carry out 3 times per week during 12 weeks for intervention arm

Primary outcomes

Systolic arterial blood pressure assessed by 24-hours home blood pressure monitoring (To baseline at 12 weeks)

Eligibility information

Inclusion Criteria: * Patient with an obstructive sleep apnea (apnea-hypopnea index \> or equal to 15) * Patient with resistant hypertension uncontrolled by 3 or more antihypertensive agents * Ambulatory patient Exclusion Criteria: * Acute hepatic failure, biliary cirrhosis, cholestasis * Acute hypertension (SBP\>= 180 mmHg and/or DBP \>= 110 mmHg) * Contraindication to CPAP treatment

Study locations

Institut Universitaire de Cardiologie et de Pneumologie de Québec (IUCPQ), Québec, Canada
Hopital Universitaire de Grenoble, La Tronche, 38700 France
Clinique Pasteur, Toulouse, 31300 France
Hopitaux Universitaires de Genève, Geneva, Switzerland
Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland

Before you participate: Varda Clinical is an independent discovery tool, not the study sponsor or a medical provider. Eligibility can only be determined by the official study team. Discuss potential risks and benefits with a qualified healthcare professional.

Source: ClinicalTrials.gov. Record last refreshed by Varda Clinical: 2026-09-27.