Recruiting

PIERS and BIS, sFIT:PIGF, Adrenomedullin

Pre-eclampsia, more than being proteinuric gestational hypertension alone, is a state of exaggerated systemic inflammation and remains a leading direct cause of maternal morbidity and mortality worldwide.1 Standardization of antenatal and postnatal assessment and surveillance of pre-eclampsia with protocols that recognize the systemic inflammatory model of preeclampsia have been associated with reduced maternal morbidity.

ClinicalTrials.gov IDNCT02578810

PhaseNot Applicable

Enrollment48

SponsorSuez Canal University

Age18 Years – 50 Years

SexFEMALE

I'm interested View official listing

Conditions studied

Eclampsia

About this study

Primary outcomes

Decline in BIS (we will record Bispectral Index (BIS) for a quite 20 min no tactile contact or noise that could raise the BIS inadvertently)

Eligibility information

Inclusion Criteria 1. Pregnancy at any stage (3 trimesters) 2. Eclampsia (Frank eclampsia) will be the crux of the study 3. Pre-eclampsia that is suspected will end up with Frank Eclampsia Exclusion criteria: 1. Any neurological conditions that can alter the electroencephalography like epilepsy 2. Any medical conditions that can alter the electroencephalography like hypoglycemia

Study locations

Medical Ethics Committee, University Malaya Medical Centre, Kuala Lumpur, Malaysia

Before you participate: Varda Clinical is an independent discovery tool, not the study sponsor or a medical provider. Eligibility can only be determined by the official study team. Discuss potential risks and benefits with a qualified healthcare professional.

Source: ClinicalTrials.gov. Record last refreshed by Varda Clinical: 2026-10-16.