MammaPrint, BluePrint, and Full-genome Data Linked With Clinical Data to Evaluate New Gene EXpression Profiles
The FLEX Registry will be implemented to operate as a large-scale, population based, prospective registry. All patients with stage I to III breast cancer who receive MammaPrint® and BluePrint testing on a primary breast tumor are eligible for entry into the FLEX Registry, which is intended to enable additional study arms at low incremental effort and cost. FLEX Registry will utilize an adaptive design, where additional targeted substudies and arms can be added after the initial study is opened.
Conditions studied
Breast Cancer
About this study
The FLEX Registry will be implemented to operate as a large-scale, population based, prospective registry. All patients with stage I to III breast cancer who receive MammaPrint® and BluePrint testing on a primary breast tumor are eligible for entry into the FLEX Registry, which is intended to enable additional study arms at low incremental effort and cost. FLEX Registry will utilize an adaptive design, where additional targeted substudies and arms can be added after the initial study is opened.
Interventions
- Diagnostic Test: MammaPrint, BluePrint, and Full-Genome Testing — Agendia will run MammaPrint and BluePrint tests using the full genome testing array.
Primary outcomes
- A large scale registry of full genome expression data to investigate new gene associations with prognostic and/or predictive value will be created. (10 years)
- A shared registry infrastructure to examine smaller groups of interest. (10 years)
Eligibility information
Study locations
- CHS Grandview, Birmingham, Alabama 35243 United States
- Providence Alaska Medical Center, Anchorage, Alaska 99508 United States
- Arizona Oncology Associates, PC, Phoenix, Arizona 85006 United States
- Arizona Oncology Associates, PC - HOPE, Tucson, Arizona 85704 United States
- Adventist Health - Bakersfield, Bakersfield, California 93301 United States
- Comprehensive Cancer Center at Desert Regional Medical Center, Palm Springs, California 92262 United States
- North Valley Breast Clinic, Redding, California 96001 United States
- UCSF Breast Care Center, San Francisco, California 94158 United States
- Valley Breast Care, Van Nuys, California 91405 United States
- Rocky Mountain Cancer Centers, Aurora, Colorado 80012 United States
Showing 10 of 134 reported sites. See the official listing for all locations.
Source: ClinicalTrials.gov. Record last refreshed by Varda Clinical: 2026-10-27.