Improving Quality of Life for Patients With Breast Cancer Invading the Chest Wall: A Prospective Registry For Patients Undergoing Full Thickness Chest Wall Resection

Conditions studied

Breast Cancer

About this study

Although chest wall recurrence of breast cancer is uncommon, it represents a difficult clinical scenario. The role of full thickness chest wall resection (FTCWR) for breast cancer recurrence in the chest wall is controversial and is complicated by the fact that no prospective evidence exists evaluating the utility of FTCWR in prolonging survival or improving health related quality of life (HRQOL) and thus, there is a lack of evidence to guide treatment decisions. Gathering HRQOL, local-regional recurrence (LRR) and survival data in a prospective fashion is thus critical in this population. Therefore, we designed a prospective trial to evaluate the outcomes for FTCWR in terms of LRC and HRQOL, and short-term morbidity and mortality, with secondary focus on potential long-term overall survival benefit.

Interventions

• Other: FACT-B and Brief Pain Inventory — Quality of Life Questionnaires

Primary outcomes

• differences in Functional Assessment of Cancer Therapy - Breast (FACT-B) scale scores (from baseline to 6 month evaluation)

Eligibility information

Study locations

• University Health Network (Toronto General Hospital and Princess Margaret Cancer Centre), Toronto, Ontario M5G 2C4 Canada