Berlin-Brandenburg Pregnancy Cohort
This study will investigate the interplay of different immune cells and placental cells as well as their potential for the development of pregnancy complications. In particular, the translation of the uteroplacental syndrome into a maternal syndrome, considered in the multifactorial pregnancy disorder preeclampsia, will be investigated. Immune cell subtypes are causally involved in the formation and translation of preeclampsia by inducing an endothelial dysfunction which leads to cardiovascular damage.
Conditions studied
Preeclampsia, Pregnancy Complications, Diabetes Mellitus in Pregnancy
About this study
This study will investigate the interplay of different immune cells and placental cells as well as their potential for the development of pregnancy complications. In particular, the translation of the uteroplacental syndrome into a maternal syndrome, considered in the multifactorial pregnancy disorder preeclampsia, will be investigated. Immune cell subtypes are causally involved in the formation and translation of preeclampsia by inducing an endothelial dysfunction which leads to cardiovascular damage.
Primary outcomes
- T cell population content at the time of preeclampsia diagnosis compared to controls and verified by flow cytometry (at the time of preeclampsia diagnosis compared to controls at the same time point in pregnancy)
Eligibility information
Study locations
- Experimental and Clinical Research Center (ECRC), Berlin, 13125 Germany
Source: ClinicalTrials.gov. Record last refreshed by Varda Clinical: 2026-10-19.