Recruiting
Treating Depression on a Day-to-day Basis: Development of a Tool for Physicians Based on a Smartphone Application
Testing and validating an e-health (smartphone application) approach to better understand the determinants of day-to-day symptomatology in depression, medication adherence, and treatment efficacy in the goal of maximizing patient care.
ClinicalTrials.gov IDNCT03678194
PhaseNA
Enrollment200
SponsorCentre Hospitalier Charles Perrens, Bordeaux
Age18 Years
SexALL
Conditions studied
Depression, Psychiatric Disorder, Brain Diseases, Central Nervous System Diseases, Nervous System Diseases
About this study
Testing and validating an e-health (smartphone application) approach to better understand the determinants of day-to-day symptomatology in depression, medication adherence, and treatment efficacy in the goal of maximizing patient care.
Interventions
- Device: Smartphone Support System — 6 weeks smartphone application with daily evaluations
Primary outcomes
- A greater clinical response in the active group (smartphone application) comparatively to the comparator group (clinical response was defined as a decline in HDRS-17 score greater than 50%) (Baseline (pre-treatment). 8 weeks post-baseline)
Eligibility information
Inclusion Criteria:
* Age between 18 and 65 years;
* Fulfilling the Diagnostic and Statistical Manual version IV (DSM-IV) criteria of depression assessed by the Structured Clinical Interview;
* Patients started their antidepressant treatment less than 5 days before inclusion;
* Patient treated in an outpatient setting;
* Patient informed of the diagnosis of his disease;
* Informed patient with written consent.
Exclusion Criteria:
* A current mental or psychiatric impairment or disease (schizophrenia, bipolar disorder) that required psychotropic medication or inpatient treatment on a psychiatric ward;
* A history of psychosis, including schizophrenia, bipolar I or bipolar II disorder, and major depressive disorder with psychotic features;
* Cognitive deficit and not thus being able to comprehend the informed consent and study procedure;
* Patients with somatic, cognitive or other disorders preventing the use of the device (deafness, impaired vision, illiteracy….);
* Non-comprehension of the French language
Study locations
- Centre Hospitalier Charles PERRENS, Bordeaux, 33076 France
Before you participate: Varda Clinical is an independent discovery tool, not the study sponsor or a medical provider. Eligibility can only be determined by the official study team. Discuss potential risks and benefits with a qualified healthcare professional.
Source: ClinicalTrials.gov. Record last refreshed by Varda Clinical: 2026-09-27.