Recruiting

Prospective Breast Cancer Biospecimen Collection

Tissue will be procured during a standard of care procedure the patient will already be scheduled to undergo. A one time blood draw will be performed at this time and an optional rectal swab for biome analysis may occur. Follow Up will only consist of chart review to determine date of recurrence, metastases, and/or death

ClinicalTrials.gov IDNCT04074720

PhaseNot Applicable

Enrollment200

SponsorThomas Jefferson University

Age18 Years

SexALL

I'm interested View official listing

Conditions studied

Breast Cancer, Invasive Breast Cancer, Carcinoma in Situ of the Breast

About this study

Interventions

Procedure: Tissue Sample collection — Tissue sample collected following standard of care procedure patient was already scheduled to have
Other: Blood Sample Collection — A one time sample of blood will be collected on day of standard of care procedure
Other: Rectal Swab — optional rectal swab may be collected on day of standard of care procedure

Primary outcomes

Tumor biomarker identification (Up to 5 years)

Eligibility information

Inclusion Criteria: * Adults \>18 years old at time of consent * Subject must be capable to giving informed consent or have an acceptable surrogate capable of giving consent on the subject behalf. * Patients with carcinoma in situ or invasive breast cancer * Patient must be undergoing one of the following: * definitive surgical tumor resection for breast cancer OR * placement of a vascular access device as a prelude to neoadjuvant therapy for breast cancer OR * neurosurgical resection of a brain metastasis from primary breast cancer. Exclusion Criteria: * \<18 years old * Not able to give informed consent and does not have acceptable surrogate capable to giving informed consent. * Active drug/alcohol dependence or abuse history

Study locations

Sidney Kimmel Cancer Center at Thomas Jefferson University, Philadelphia, Pennsylvania 19107 United States

Before you participate: Varda Clinical is an independent discovery tool, not the study sponsor or a medical provider. Eligibility can only be determined by the official study team. Discuss potential risks and benefits with a qualified healthcare professional.

Source: ClinicalTrials.gov. Record last refreshed by Varda Clinical: 2026-09-27.