The Sunnybrook Type 2 Diabetes Study
The Sunnybrook Type 2 Diabetes Study (S2DS) is a prospective observational study of people with prediabetes or Type 2 Diabetes Mellitus (T2DM), that aims to understand the aetiologies, manifestations, and clinical consequences of mood and cognitive complications. The study recruits from the services at Sunnybrook Health Sciences Centre and from the neighbouring University Health Network Toronto Rehabilitation Institute Cardiac Rehabilitation Program.
Conditions studied
Type 2 Diabetes, PreDiabetes
About this study
The Sunnybrook Type 2 Diabetes Study (S2DS) is a prospective observational study of people with prediabetes or Type 2 Diabetes Mellitus (T2DM), that aims to understand the aetiologies, manifestations, and clinical consequences of mood and cognitive complications. The study recruits from the services at Sunnybrook Health Sciences Centre and from the neighbouring University Health Network Toronto Rehabilitation Institute Cardiac Rehabilitation Program.
Interventions
- Behavioral: Diabetes Exercise and Healthy Lifestyle Program — The program combines exercise, education and healthy lifestyle behaviour changes. Participants will begin the program with a cardiopulmonary exercise assessment. Then the team will create a personalized program of exercise based on functional abilities and personal goals. Participants will attend 1 supervised exercise class a week, which includes a warm-up and stretching routine, aerobic exercise (walking, stationary cycling or elliptical machine), resistance training and an educational session. This program also offers peer-to-peer support and encourages participants to carry out their own exercise program at home 4 more times per week and to keep a weekly exercise diary to help them with their progress.
- Other: Outpatient care — Participants receive usual care from outpatient services, which may include Endocrinology, Family Medicine, or Diabetes Education
Primary outcomes
- Depressive episode (6 Months)
- Neuropsychological function (6 Months)
Eligibility information
Study locations
- Sunnybrook Research Institute, Toronto, Ontario M4N 3M5 Canada
Source: ClinicalTrials.gov. Record last refreshed by Varda Clinical: 2026-10-05.