Predicting Acute-on-Chronic Liver Failure After Surgical Intervention in Chronic Liver Disease

Inclusion Criteria: * Male or female adult (≥18 years) patient * With or without liver cirrhosis (diagnosed either histologically or by a combination of clinical, laboratory and radiological signs) * Or Non-cirrhotic portal hypertension * Non-pregnant, non-lactating females * Ability to understand the patient information and to personally sign and date the informed consent to participate in the study * The patient is co-operative and available for the entire study * Provided written informed consent * Indication for surgical intervention Exclusion Criteria: * Pregnant or lactating females * Patients undergoing surgery as form of palliative cancer therapy * Presence or history of severe extra-hepatic diseases * HIV-positive patients * Previous liver or other transplantation * Patients with acute or subacute liver failure without underlying cirrhosis * Patients who decline to participate * Physician´s denial (e.g. the investigator considers that the patient will not follow the protocol scheduled)