Recruiting
Effect of Bariatric Surgery on Cardiac Function in Patients With Hypertension
The purpose of this study is to investigate the effect of bariatric surgery on cardiac function assessed by echocardiography in patients with hypertension.
ClinicalTrials.gov IDNCT05166954
PhaseNot Applicable
Enrollment40
SponsorBeijing Friendship Hospital
Age17 Years
SexALL
Conditions studied
Bariatric Surgery, Hypertension
About this study
The purpose of this study is to investigate the effect of bariatric surgery on cardiac function assessed by echocardiography in patients with hypertension.
Interventions
- Procedure: LSG — Laparoscopic sleeve gastrectomy (LSG) together with medical treatment aiming the control of cardiovascular risks including hypertension, diabetes mellitus or dyslipidemia.
- Procedure: RYGB — Roux-en-Y gastric bypass (LRYGB) together with medical treatment aiming the control of cardiovascular risks including hypertension, diabetes mellitus or dyslipidemia.
Primary outcomes
- Changes on left ventricular ejection fraction (LVEF) (12 months)
Eligibility information
Inclusion Criteria:
* 18-70 years old
* BMI\>24kg/m2
* Bariatric surgery patients of Beijing Friendship Hospital
* History of hypertension and treated with ≥2 antihypertensive drugs for more than 4 weeks
* No major barriers to provide written consent
Exclusion Criteria:
* Secondary hypertension, except because of sleep apnea
* cardiovascular disease (myocardial infarction, heart failure, stroke or coronary revascularization) within 6 months
* Severe concomitant diseases (autoimmune disease, malignancy, late stage of liver diseases, respiratory diseases and digestive diseases)
* Unable to understand or comply with the study procedures
Study locations
- Beijing Friendship Hospital, Capital Medical University, Beijing, Beijing Municipality 100050 China
Before you participate: Varda Clinical is an independent discovery tool, not the study sponsor or a medical provider. Eligibility can only be determined by the official study team. Discuss potential risks and benefits with a qualified healthcare professional.
Source: ClinicalTrials.gov. Record last refreshed by Varda Clinical: 2026-09-27.