Recruiting
Office, Home, and Ambulatory Blood Pressure
This will be a prospective observational study. The population would be pediatric patients 6 years to \<19 years of age who were referred for elevated blood pressure to investigate if home blood pressure (HBP) can determine blood pressure phenotype (normotensive, hypertensive, masked hypertension, white coat hypertension) as accurately as ambulatory blood pressure monitor (ABPM) in childhood and adolescence.
ClinicalTrials.gov IDNCT05297708
PhaseNot Applicable
Enrollment52
SponsorChildren's Hospital Medical Center, Cincinnati
Age6 Years
SexALL
Conditions studied
Elevated Blood Pressure
About this study
This will be a prospective observational study. The population would be pediatric patients 6 years to \<19 years of age who were referred for elevated blood pressure to investigate if home blood pressure (HBP) can determine blood pressure phenotype (normotensive, hypertensive, masked hypertension, white coat hypertension) as accurately as ambulatory blood pressure monitor (ABPM) in childhood and adolescence.
Primary outcomes
- Determine blood pressure phenotype (6-12 months after enrollment)
Eligibility information
Inclusion Criteria:
1. Age 6 years to \<19 years old;
2. Elevated blood pressure defined as 15% lower than the 95%ile BP based on clinical practice guidelines(CPG) but less than stage II hypertension based on CPG;
3. Tolerate ABPM 24 hours;
4. Tolerate HBP; and
5. Can have diabetes mellitus, obstructive sleep apnea, and attention deficit hyperactivity disorder managed by medication.
6. On stable doses of medications known to affect BP such as:
1. Corticosteroids
2. Calcineurin inhibitors
3. Oral decongestants;
7. Clinically stable
Exclusion Criteria:
1. On antihypertension medications or treated in the last 6 months;
2. Pregnant;
3. Structural heart disease such as:
1. Obstructive valvular disease
2. Coarctation of the aorta
3. Cardiomyopathy;
4. Other secondary causes such as:
1. Renal artery stenosis
2. Neurological condition with dysautonomia;
5. Recent initiation of medications known to affect BP such as:
1. Corticosteroids
2. Calcineurin inhibitors
3. Oral decongestants;
Study locations
- Cincinnati Children's Hospital, Cincinnati, Ohio 45229 United States
Before you participate: Varda Clinical is an independent discovery tool, not the study sponsor or a medical provider. Eligibility can only be determined by the official study team. Discuss potential risks and benefits with a qualified healthcare professional.
Source: ClinicalTrials.gov. Record last refreshed by Varda Clinical: 2026-09-27.