Recruiting

Improving the Collaborative Health of Adult Dyads

This study tests the efficacy of a dyadic intervention to mitigate the adverse health consequences of adults with pre-existing chronic health conditions and their informal carepartners (IC). Socioeconomically disadvantaged, older, and people from rural regions are more likely burdened with greater rates of chronic diseases such as diabetes, hypertension, chronic kidney disease, cardiovascular disease, and stroke.

ClinicalTrials.gov IDNCT05370014

PhaseNA

Enrollment500

SponsorUniversity of South Carolina

Age18 Years

SexALL

I'm interested View official listing

Conditions studied

Cardiovascular Diseases, Chronic Kidney Diseases, Diabetes Mellitus, Type 2, Chronic Disease, Stroke, Heart Failure Chronic, Hypertension (HTN)

About this study

Interventions

Behavioral: Integrating Community-based Intervention Under Nurse Guidance with Families (iCINGS FAM) — The intervention consists of two planning sessions with the dyad (over 2 weeks) followed by eight topic-guided sessions delivered the RN-CHW team over 12 weeks (weekly the first 4 weeks, then bi-weekly) (Table 3). Key components of these televisits include risk mitigation, chronic disease management, medication adherence, family functioning/support, and community and health systems resource identification and referral with ongoing goal planning. The RN-CHW will meet weekly for progress review, follow up planning, and setting up anticipatory guidance for the next session with the dyads. The RN and CHW will also review IC or survivor dissatisfaction and other issues that require more immediate attention. RN-CHW planning will be assessed to make sure each televisit remain topic focused yet incorporates flexibility to suit the needs of each dyad.

Primary outcomes

Change in patient-reported outcomes measurement information system (PROMIS) Global Health Scale (0, 4, 7 months)

Eligibility information

Inclusion Criteria: * Male and female * Living in a Medically Underserved Area and/or a designated rural area of South Carolina * ≥ 18 years and above * A previous diagnosis of one or more of the following conditions: type 2 diabetes, hypertension, cardiovascular disease, chronic kidney disease, or stroke (\>3 months) -Carepartner inclusion criteria * Male and female * ≥ 18 years and above * Must live on the same property or community, preferably within a 40-mile radius of the patient (dyad member) * Primarily responsible for care provision and/or care/social support in the home (i.e., is not paid for services) Exclusion Criteria: • Enrolled in related clinical trials .No member of dyad has at least one of the included chronic health conditions

Study locations

University of South Carolina, Columbia, South Carolina 29208 United States

Before you participate: Varda Clinical is an independent discovery tool, not the study sponsor or a medical provider. Eligibility can only be determined by the official study team. Discuss potential risks and benefits with a qualified healthcare professional.

Source: ClinicalTrials.gov. Record last refreshed by Varda Clinical: 2026-09-27.