Liver Fat as a Dietary Target of the Chinese Medical Nutrition Therapy (CMNT) Diet for Treating Type 2 Diabetes With Nonalcoholic Fatty Liver Disease
Type 2 diabetes (T2D) represents a serious public health problem. Patients with T2D and non-alcoholic fatty liver disease(NAFLD) demonstrate a poor metabolic profile and increase mortality compared with patients with only NAFLD or T2D. Nutritional intervention is the most basic treatment for T2D. Previous study showed that a Chinese medical nutrition therapy (CMNT) diet, which intermittent use of low-calorie medicinal food, has a glucose-lowering effect in T2D. This study aims to investigate the effect of a…
Conditions studied
Type 2 Diabetes
About this study
Type 2 diabetes (T2D) represents a serious public health problem. Patients with T2D and non-alcoholic fatty liver disease(NAFLD) demonstrate a poor metabolic profile and increase mortality compared with patients with only NAFLD or T2D. Nutritional intervention is the most basic treatment for T2D. Previous study showed that a Chinese medical nutrition therapy (CMNT) diet, which intermittent use of low-calorie medicinal food, has a glucose-lowering effect in T2D. This study aims to investigate the effect of a Chinese medical nutrition therapy (CMNT) diet accompanied by intermittent energy restriction on reducing liver fat and glycated hemoglobin (HbA1c) in patients with T2D and NAFLD.
Interventions
- Other: CMNT diet — Hypocaloric CMNT diet plan: A diet plan with intermittent use of enriched traditional-Chinese-medicinal-foods CMNT diet
Primary outcomes
- Controlled attenuation parameter (CAP) value by transient elastography (3, 6, 12, 24 months)
- HbA1C (3, 6, 12, 24 months)
Eligibility information
Study locations
- Physical Examination Center of Gezhouba central hospital of Sinopharm, Yichang, Hubei China
- Hunan Shanshui physical examination center, Changsha, Hunan China
- Jinheyuan Outpatient Department, National Sub-health Intervention Technology Achievement Application Center, Changsha, Hunan China
Source: ClinicalTrials.gov. Record last refreshed by Varda Clinical: 2026-09-28.