Recruiting
Technology-enabled Management Versus Usual Care for Blood Pressure
Two arm parallel randomized clinical trial
ClinicalTrials.gov IDNCT05479461
PhaseNA
Enrollment200
SponsorStanford University
Age30 Years
SexALL
Conditions studied
Hypertension
About this study
Two arm parallel randomized clinical trial
Interventions
- Other: Digital Hypertension Management System — Mobile health technology using physician- directed, semi-automated management of hypertension
- Other: Usual Care — The participants will receive usual care
Primary outcomes
- Defined Daily Dose (DDD) (Visit 1 (Baseline), Visit-3 (6 Month follow up))
Eligibility information
Inclusion Criteria:
* Age 30-90 yrs.
* Smartphone ownership
* Office SBP: ≥ 140 mm Hg
* ≤ 2 current anti-HTN meds
* Able to add or dose-increase at least 2 of the following classes of medications: ACE-I/ARB, diuretic, calcium channel blocker, beta-blocker, mineralocorticoid receptor antagonists (i.e., at least 2 classes are available for addition or dose- increases after excluding intolerant medications and medications currently at maximum dose)
* English or Spanish-speakers
Exclusion Criteria:
* Heart failure with reduced ejection fraction (EF \< 40%)
* ESRD (GFR \<15)
* Renal replacement therapy
* Pregnant
* Myocardial infarction or stroke within preceding 6 months
* Hospitalization for hypertensive emergency or malignant hypertension within preceding 6 months
* Prior solid organ transplantation
* At the clinical discretion of the investigators
* Enrolled in another clinical study
Study locations
- Stanford Health Care, Palo Alto, California 94305 United States
- Morehouse School of Medicine, Atlanta, Georgia 30310 United States
- Lake Country Medical Group, Eatonton, Georgia 31024 United States
Before you participate: Varda Clinical is an independent discovery tool, not the study sponsor or a medical provider. Eligibility can only be determined by the official study team. Discuss potential risks and benefits with a qualified healthcare professional.
Source: ClinicalTrials.gov. Record last refreshed by Varda Clinical: 2026-09-27.