Recruiting

The eHealth Diabetes Remission Trial

Overweight patients with type 2 diabetes are offered a total diet replacement with the goal of weight loss and diabetes remission. Study participants are randomised to eHealth follow-up or face-to-face follow-up, but the dietary advice is the same in both groups. A healthy control group with normal glucose tolerance is examined once but is not randomised and does not receive any intervention.

ClinicalTrials.gov IDNCT05491005

PhaseNA

Enrollment106

SponsorUmeå University

Age20 Years

SexALL

I'm interested View official listing

Conditions studied

Diabetes Mellitus, Type 2

About this study

Interventions

Behavioral: Total diet replacement — Total diet replacement (850 kcal/day) for 3 months followed by weight maintenance for 21 months.
Behavioral: eHealth — All follow-up through an eHealth application and video meetings.
Behavioral: Face-to-face — All follow-up through face-to-face meetings.

Primary outcomes

HbA1c (12 months)

Eligibility information

Inclusion Criteria: * Type 2 diabetes with duration 0-6 years * BMI 27 kg/m2 and higher * HbA1c 43 mmol/mol or higher (48 or higher if without diabetes medication) Exclusion Criteria: * Insulin treatment * Weight loss more than 5 kg during the past 6 months * Diagnosed eating disorder * eGFR \< 30 ml/min/1,73m2 * Myocardial infarction last six months * Severe heart failure (NYHA class III) * Ongoing cancer * Pregnancy * Treatment with antipsychotic drugs

Study locations

Bra Liv Råslätt vårdcentral, Jönköping, Sweden
Örnsköldsvik hospital, Örnsköldsvik, Sweden
Department of Public Health and Clinical Medicine, Medicine, Umeå, 90187 Sweden

Before you participate: Varda Clinical is an independent discovery tool, not the study sponsor or a medical provider. Eligibility can only be determined by the official study team. Discuss potential risks and benefits with a qualified healthcare professional.

Source: ClinicalTrials.gov. Record last refreshed by Varda Clinical: 2026-09-27.