Recruiting
Pre-operative Therapy in Breast Cancer
This is a prospective and retrospective study to evaluate the effect of pre-operative therapy on response and survival, and compare the difference in response and survival by pre-operative regimen or by patient's clinicopathological characteristic in early or advanced breast cancer.
ClinicalTrials.gov IDNCT05621564
PhaseNot Applicable
Enrollment6032
SponsorRenJi Hospital
Age18 Years
SexFEMALE
Conditions studied
Breast Cancer
About this study
This is a prospective and retrospective study to evaluate the effect of pre-operative therapy on response and survival, and compare the difference in response and survival by pre-operative regimen or by patient's clinicopathological characteristic in early or advanced breast cancer.
Interventions
- Drug: pre-operative therapy — pre-operative therapy includes pre-operative chemotherapy, radiation, endocrine therapy, target therapy and other anti-tumor therapy
Primary outcomes
- Pathologic Complete Response (at surgery)
Eligibility information
Inclusion Criteria:
* Female, Aged ≥18 years
* Histologically confirmed primary breast cancer
* Plan to receive pre-operative therapy
* Adequate organ function
Exclusion Criteria:
* History of neurological or psychological disease, including epilepsy or dementia
* Not suitable to participate in this study judged by investigators
Study locations
- Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, 200127 China
Before you participate: Varda Clinical is an independent discovery tool, not the study sponsor or a medical provider. Eligibility can only be determined by the official study team. Discuss potential risks and benefits with a qualified healthcare professional.
Source: ClinicalTrials.gov. Record last refreshed by Varda Clinical: 2026-10-02.