Recruiting

International Prospective REgistry on Pre-pectorAl Breast REconstruction

This is an international multicenter prospective cohort study aimed at collecting data on breast reconstruction techniques with pre-pectoral implants after mastectomy for breast cancer. The aim of the study is to collect data on the surgical, aesthetic and oncological results, as well as on the quality of life of the patients who will undergo breast reconstruction with a pre-pectoral approach.

ClinicalTrials.gov IDNCT05817175

PhaseNot Applicable

Enrollment1236

SponsorEuropean Breast Cancer Research Association of Surgical Trialists

Age18 Years

SexFEMALE

I'm interested View official listing

Conditions studied

Breast Cancer

About this study

Interventions

Procedure: pre-pectoral breast reconstruction — to prospectively evaluate the utilization of the pre-pectoral approach, and evaluate oncological and aesthetic outcomes related to each type of surgical technique and the use of postmastectomy radiation therapy

Primary outcomes

Number of patients with Implant-loss at three months postoperatively (three months postoperatively)

Eligibility information

Inclusion Criteria: * Female patients older than 18 years old * Signed informed consent form * Patients undergoing mono or bilateral therapeutic mastectomy * Patients undergoing pre-pectoral implant-based breast reconstruction with implant or expander with or without mesh Exclusion Criteria: * Male patients * Patients not suitable for surgical treatment * Patients undergoing subpectoral reconstruction * Patients undergoing breast reconstruction with autologous tissue.

Study locations

Univesidad de Buenos Aires, Buenos Aires, Argentina
Mansoura Insurance, Al Mansurah, Egypt
Mansoura Oncology, Al Mansurah, Egypt
National ans Kapodistrian University of Athens, Athens, Greece
Ospedale San Raffaele, Milan, MI 20132 Italy
Fondazione Policlinico Universitario Agostino Gemelli, Roma, RM 00136 Italy
University Hospital of Karol Marcinkowski, Zielona Góra, Poland
Prof. Dr. Ion Chiricuta Institute of Oncology, Cluj-Napoca, Romania
Hospital del Mar, Barcelona, Spain
Marmara University School of medicine, Istanbul, Turkey (Türkiye)

Showing 10 of 11 reported sites. See the official listing for all locations.

Before you participate: Varda Clinical is an independent discovery tool, not the study sponsor or a medical provider. Eligibility can only be determined by the official study team. Discuss potential risks and benefits with a qualified healthcare professional.

Source: ClinicalTrials.gov. Record last refreshed by Varda Clinical: 2026-09-27.