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Prediction on the Recurrence of Manic and Depressive Episodes in Bipolar Disorder

Mood disorders (including bipolar disorder and major depressive disorder) are chronic mental disorders with high recurrent rate. The more the number of recurrence is, the worse long-term prognosis is. This study aims to establish a prediction model of recurrence of manic and depressive episodes in mood disorders, with a hope to detect recurrence relapse as early as possible for timely clinical intervention. We will adopt wearable smart watch to collect heart rate, sleep pattern, activity level, as well as…

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ClinicalTrials.gov IDNCT05828056
PhaseNot Applicable
Enrollment100
SponsorNational Taiwan University Hospital
Age20 Years – 60 Years
SexALL
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Conditions studied

Bipolar Disorder, Depressive Disorder

About this study

Mood disorders (including bipolar disorder and major depressive disorder) are chronic mental disorders with high recurrent rate. The more the number of recurrence is, the worse long-term prognosis is. This study aims to establish a prediction model of recurrence of manic and depressive episodes in mood disorders, with a hope to detect recurrence relapse as early as possible for timely clinical intervention. We will adopt wearable smart watch to collect heart rate, sleep pattern, activity level, as well as emotional status for one year long in 100 patients with bipolar disorder, and annotated their mood status (i.e., manic episode, depressive episode, and euthymic state). We expect to establish prediction models to predict the recurrence of mood episodes.

Interventions

Primary outcomes

Eligibility information

Inclusion Criteria: * DSM-5 Bipolar disorder or depressive disorder * 20\~60 years old * Willing to carry smartwatch and smartphone most of the time Exclusion Criteria: * Comorbid with substance use disorder * Unable to use smartwatch and smartphone

Study locations

Before you participate: Varda Clinical is an independent discovery tool, not the study sponsor or a medical provider. Eligibility can only be determined by the official study team. Discuss potential risks and benefits with a qualified healthcare professional.

Source: ClinicalTrials.gov. Record last refreshed by Varda Clinical: 2026-11-06.