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Preventing Suicide Among Sexual and Gender Diverse Young Adults in Primary Care

The overall aim of this study is to reduce suicide among sexual and gender diverse youth ages 18-24 years old. This study will compare the effectiveness of two brief suicide prevention interventions that have been adapted for use with this population to use in primary care via telehealth and will recruit youth from primary care clinics in multiple metropolitan areas. The primary study outcome is suicidal ideation. Each clinic will be randomly assigned to deliver one of the two study interventions.

ClinicalTrials.gov IDNCT05869552

PhaseNA

Enrollment1485

SponsorElizabeth Arnold

Age18 Years

SexALL

I'm interested View official listing

Conditions studied

Suicide, Suicidal Ideation

About this study

Interventions

Other: STAT-PC — STAT-PC is an adapted version of Suicidal Teens Accessing Treatment after an ED Visit (STAT-ED). It is a brief intervention based on motivational interviewing (MI) that focuses on mental health care seeking behavior, problem-solving, and referrals plus brief case management. The intervention will consist of an initial session with the youth focusing on accessing mental health care plus case management calls. The interventionist will also be available to assist with referrals for connection to other services later during the study period as needed for up to three months. The intervention may include contact with the youth's mental health provider to make sure linkages are made.
Other: YST-III — YST-III is an adapted version of Youth-Nominated Support Team for Suicidal Adolescents (YST-II). The intervention is a brief intervention originally developed for youth who have been psychiatrically hospitalized due to a suicide attempt or suicidal ideation (SI). Participants will nominate supportive adults (age 18 and older) from their lives who agree to provide ongoing contact and support for up to 3 months. YST-III will include an introductory session with the youth who will nominate their support persons plus referrals for mental health services. The support persons will receive training and support on how to best support their youth partner and then ongoing calls to support them in working with their youth partner for up to 3 months.

Primary outcomes

Change in suicidal ideation as measured by the Adult Suicidal Ideation Questionnaire (ASIQ) (baseline and months 1, 3, 6)

Eligibility information

Inclusion Criteria: * be aged 18-24 at the time of enrollment * not have received mental health services in the past 90 days, excluding medication and case management * English-speaking * screen positive for suicide risk Exclusion Criteria: * are actively suicidal * have a developmental disability that would preclude them from participating in the study intervention * who are impaired due to psychosis, mania, or substance use that would prevent them from providing consent. * Participants will also be excluded at YST-III sites if they are unable to identify a minimum of one support person to participate in the intervention with them

Study locations

University of Pittsburgh, Pittsburgh, Pennsylvania 15261 United States
Steve Hicks School of Social Work at the University of Texas at Austin, Austin, Texas 78705 United States
University of Texas Southwestern Medical Center, Dallas, Texas 75390 United States

Before you participate: Varda Clinical is an independent discovery tool, not the study sponsor or a medical provider. Eligibility can only be determined by the official study team. Discuss potential risks and benefits with a qualified healthcare professional.

Source: ClinicalTrials.gov. Record last refreshed by Varda Clinical: 2026-09-27.