Recruiting

The Daytime Circadian Rhythm in Exhaled Volatile Organic Compounds in People Living Without and Diabetes

Exhaled volatile organic compounds will be measured during daytime with the goal to identifying circadian variability. The study incudes three subgroups: people without diabetes, people with type 1 diabetes, and people with type 2 diabetes. A total of 60 people will be recruited for the study.

ClinicalTrials.gov IDNCT05984979
PhaseNot Applicable
Enrollment60
SponsorUniversity of Bern
Age18 Years and older
SexALL
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Conditions studied

Diabetes Mellitus

About this study

Exhaled volatile organic compounds will be measured during daytime with the goal to identifying circadian variability. The study incudes three subgroups: people without diabetes, people with type 1 diabetes, and people with type 2 diabetes. A total of 60 people will be recruited for the study.

Interventions

Primary outcomes

Eligibility information

Inclusion criteria Subgroup 1: * Age 18 or older * HbA1c below 6.5% * Written informed consent Subgroup 2: * Age 18 or older * T1D (Type 1 diabetes) with MDI (multiple daily injection) or CSII (Continuous subcutaneous insulin infusion therapy) therapy \>1 year * Written informed consent Subgroup 3 * Age 18 or older * T2D (Type 2 diabetes) with oral antidiabetic medication or insulin therapy * Written informed consent Exclusion criteria * Pregnancy or breastfeeding * Smoking (last cigarette less than 6 months ago) * Any chronical lung and intestinal disease diagnosis (such as intestinal bowel disease (IBD); asthma; COPD (chronic obstructive pulmonary disease); lung cancer, …) * Coeliac disease * Lactose and fructose intolerance * Any acute disease diagnosis (such as viral or bacterial infection) * Drinking habit of more than four units of alcohol per day * Current inhaled medicines treatments * Antibiotic treatment in the previous 4 months

Study locations

Before you participate: Varda Clinical is an independent discovery tool, not the study sponsor or a medical provider. Eligibility can only be determined by the official study team. Discuss potential risks and benefits with a qualified healthcare professional.

Source: ClinicalTrials.gov. Record last refreshed by Varda Clinical: 2026-10-23.