Recruiting

To Evaluate the Clinical Efficacy of Probiotics in Patients With the Breast Cancer

Chemotherapy-associated side-effects would affect therapeutic effect, quality of life, and cause permanent harm to breast cancer patients. This study is designed to explore after consumption of probiotics of lactobacillus composite strain powder sachets for 6 months in breast cancer chemotherapy, and whether the improvement of meliorate the side effects, further assists patients completing the chemotherapy.

ClinicalTrials.gov IDNCT06039644

PhaseNA

Enrollment100

SponsorGenMont Biotech Incorporation

Age20 Years – 80 Years

SexALL

I'm interested View official listing

Conditions studied

Breast Cancer

About this study

Interventions

Dietary Supplement: Probiotic — Three-strain probiotic supplement includes Lactobacillus reuteri GMNL-89 (alive), Lactobacillus plantarum GMNL-141 (alive) and Lactobacillus paracasei GMNL-133 (alive).
Other: Placebo — Same additives to Probiotic group but replace probiotics with corn starch and Maltodextrin.

Primary outcomes

Change from 12 weeks in the chemotherapy associated side-effects questionnaire at 24 weeks (24 weeks)

Eligibility information

Inclusion Criteria: * Stage I-III breast patients using anthracycline-based and taxane-based chemotherapy (not limited before or after chemotherapy/surgery) * BMI \> 18 kg/m\^2 * Age between 20 and 80 years old * Patients judged by physicians to participate in this trial and who are willing Exclusion Criteria: * Pregnant or lactating female patients * Patients with bariatric surgery, gastrointestinal resections, Crohn's disease, celiac disease * BMI \< 18 kg/m\^2 * Patient who have severe allergy to soybeans or peanuts * Those who are under 20 years old or over 80 years old

Study locations

Mackay Memorial Hospital, Taipei, Taiwan

Before you participate: Varda Clinical is an independent discovery tool, not the study sponsor or a medical provider. Eligibility can only be determined by the official study team. Discuss potential risks and benefits with a qualified healthcare professional.

Source: ClinicalTrials.gov. Record last refreshed by Varda Clinical: 2026-10-27.