Recruiting

Blood Pressure Lowering Strategies to Eliminate Hypertension Disparities (BLESSED)

ClinicalTrials.gov IDNCT06133322

PhaseNA

Enrollment1176

SponsorTulane University

Age18 Years

SexALL

I'm interested View official listing

Conditions studied

Hypertension

About this study

The burden of hypertension and related cardiovascular diseases, stroke, and end-stage kidney disease is disproportionately high in Black populations, especially in the South. The Blood Pressure Lowering Strategies to Eliminate Hypertension Disparities (BLESSED) cluster randomized trial aims to test the effectiveness, implementation, and sustainability of a community health worker (CHW)-led multifaceted intervention compared to enhanced usual care for hypertension control in Black communities. In the BLESSED trial, the investigators plan to recruit 1,176 adults with hypertension (approximately 28 per church) from 42 predominantly Black churches in the Greater New Orleans area. The multifaceted intervention will last for 18 months, followed by a post-intervention follow-up visit at 24 months. The BLESSED trial aims to generate evidence regarding the effectiveness, implementation, and sustainability of this CHW-led church-based multifaceted intervention in eliminating hypertension disparities in the United States (US) general population.

Interventions

Behavioral: Behavioral: Evidence-based interventions recommended by the 2017 ACC/AHA hypertension clinical guideline — The recommended evidence-based interventions include therapeutic lifestyle change and medical treatment of hypertension

Primary outcomes

Difference in mean change of systolic blood pressure (Measured from baseline to 18 months)
Implementation fidelity summary score (Measured at 6, 12, and 18 months)

Eligibility information

Inclusion Criteria: 1. Men or women aged ≥18 years 2. Community members associated with the participating churches (church members and their families and friends) 3. Systolic blood pressure ≥130 mmHg or diastolic blood pressure ≥80 mm Hg 4. Willing and able to participate in the intervention. 5. Willing and able to sign written informed consent. Exclusion Criteria: 1. Prior hospitalization in the last 3 months for chronic heart failure or heart attack 2. Current diagnosis of cancer requiring chemotherapy or radiation therapy 3. Stage-5 chronic kidney disease requiring chronic dialysis or transplant 4. Pregnant or planning to become pregnant in the next 18 months 5. Planning to move out of the Greater New Orleans area during the next year

Study locations

Tulane University, New Orleans, Louisiana 70112 United States

Before you participate: Varda Clinical is an independent discovery tool, not the study sponsor or a medical provider. Eligibility can only be determined by the official study team. Discuss potential risks and benefits with a qualified healthcare professional.

Source: ClinicalTrials.gov. Record last refreshed by Varda Clinical: 2026-09-27.