Recruiting
Nutrition for Asthmatics
Determine to what extent three distinct dietary approaches improve asthma control and lung function.
ClinicalTrials.gov IDNCT06151405
PhaseNA
Enrollment15
SponsorPennington Biomedical Research Center
Age18 Years
SexALL
Conditions studied
Asthma
About this study
Determine to what extent three distinct dietary approaches improve asthma control and lung function.
Interventions
- Other: DGA Diet — A fully provisioned isocaloric, isonitrogenous study diet following the Dietary Guidelines for Americans (DGA) Including: * A variety of vegetables and fruits * Grains, at least half of which are whole grains * Fat-free or low-fat dairy * A variety of protein foods, including seafood, lean meats and poultry, eggs, legumes, nuts, and seeds * This healthy eating pattern also limits saturated fats and trans fats, added sugars, and sodium.
- Other: MCT Diet — A fully provisioned isocaloric, isonitrogenous study diet following the Dietary Guidelines for Americans supplemented with medium chain triglycerides (MCT).
- Other: KETO Diet — A fully provisioned isocaloric, isonitrogenous ketogenic study diet.
Primary outcomes
- Asthma Control (Baseline)
- Asthma Control (After 7 days on Diet#1)
- Asthma Control (After 7 days on Diet#2)
- Asthma Control (After 7 days on Diet#3)
- Lung Function (Baseline)
- Lung Function (After 7 days on Diet#1)
- Lung Function (After 7 days on Diet#2)
- Lung Function (After 7 days on Diet#3)
Eligibility information
Inclusion Criteria:
* Age: 18-65 years
* BMI: 18.5 - 29.99 kg/m2
* asthma diagnosed by medical specialist (confirmed in medical history)
* partly controlled or uncontrolled asthma by Asthma Control Test score ≤22
* owns a device compatible with ZEPHYRx platform
* stable asthma medication use (no change in the past 2 months).
Exclusion Criteria:
* Diabetes or using diabetes medications that may lower blood glucose levels
* point of care fasting blood glucose ≥126 mg/dl or triglycerides ≥400 mg/dl
* current smoking or smoking history of greater than 10 pack-years
* other significant respiratory or cardiac disease or the presence of clinically important comorbidities, e.g., COPD, renal failure, liver disease; uncontrolled hypertension defined as systolic blood pressure ≥160 mm/Hg, or diastolic blood pressure ≥100 mm/Hg
* pregnant or nursing women
* food preferences or allergies inconsistent with study diet capabilities
* noncompliance with lead-in period requirements.
Study locations
- Pennington Biomedical Research Center, Baton Rouge, Louisiana 70808 United States
Before you participate: Varda Clinical is an independent discovery tool, not the study sponsor or a medical provider. Eligibility can only be determined by the official study team. Discuss potential risks and benefits with a qualified healthcare professional.
Source: ClinicalTrials.gov. Record last refreshed by Varda Clinical: 2026-09-27.