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A Comparison of Diagnostic Testing Modalities in the Assessment of Asthma
This study aims to assess the concordance of international asthma guidelines in the diagnosis of asthma and explore the presence of airways disease using additional non-guideline physiologic criteria, such as IOS (impulse osciollometry), not included in the guidelines, but available in the Portsmouth lung function service.
ClinicalTrials.gov IDNCT06286085
PhaseNot Applicable
Enrollment2000
SponsorPortsmouth Hospitals NHS Trust
Age18 Years
SexALL
Conditions studied
Asthma
About this study
This study aims to assess the concordance of international asthma guidelines in the diagnosis of asthma and explore the presence of airways disease using additional non-guideline physiologic criteria, such as IOS (impulse osciollometry), not included in the guidelines, but available in the Portsmouth lung function service.
Interventions
- Other: Lung function tests — Pulmonary function tests
Primary outcomes
- International asthma guidelines scores (during study analysis 4 weeks after recruitment)
- non-guideline physiologic criteria numbers (during study analysis 4 weeks after recruitment)
Eligibility information
Inclusion Criteria:
* The patient will meet all the following criteria to be considered eligible for the study:
* Aged 18 years or over.
* All patients who have attended full asthma workups from November 2021 till date
* Willing and able to consent to use their data in this study (opt-out form or e-consent).
* Patients referred to the Portsmouth asthma service for diagnosis and further management of presumed asthma. Comorbidities are common in asthma, thus patients with co-existing conditions such as obesity, bronchiectasis or COPD will be included.
Exclusion Criteria:
* The participant may not enter the study if either of the following apply:
* Unable to comprehend the study and provide informed consent, e.g., insufficient command of English in the absence of someone who can adequately interpret.
* Patients with other primary respiratory conditions, such as ILD.
Study locations
- Portsmouth Hospitals University NHS Trust, Portsmouth, United Kingdom
Before you participate: Varda Clinical is an independent discovery tool, not the study sponsor or a medical provider. Eligibility can only be determined by the official study team. Discuss potential risks and benefits with a qualified healthcare professional.
Source: ClinicalTrials.gov. Record last refreshed by Varda Clinical: 2026-09-28.