Subendocardial Viability Ratio in Hypertension

Conditions studied

Hypertension

About this study

The aim of the research is to evaluate the Subendocardial Viability Ratio (SEVR) in hypertensive patients, using non-invasive arterial tonometry, and to establish the influencing factors and the possibility of predicting cardiovascular morbidity and mortality in arterial hypertension. The SEVR will be evaluated on all patients belonging to the Arterial Hypertension Centers undergoing non-invasive arterial tonometry. The SEVR is calculated on the morphology of the central pressure wave as the ratio between the DPTI (diastolic pressure-time index), i.e. the area between the carotid pressure curve and the ventricular pressure curve during the diastolic phase, and the SPTI ( systolic pressure-time index), i.e. the area under the carotid pressure curve during the systolic phase. The SEVR will be correlated with the anthropometric and pathology variables which will be collected in an appropriate database.

Interventions

• Diagnostic Test: Arterial tonometry — Arterial transcutaneous tonometry

Primary outcomes

• Buckberg index (At recruitment, at 1 year, 2 years, 3 years and 4 years of follow-up)

Eligibility information

Study locations

• Centro di Prevenzione e Cura dell'Ipertensione Arteriosa "Alessandro Filippi", Mascalucia, Catania Italy
• Unità Operativa Semplice Dipartimentale Ipertensione Arteriosa "Anna Maria Pirrelli", Università degli Studi di Bari "Aldo Moro". Policlinico Consorziale di Bari, Bari, Italy
• Istituto Auxologico Italiano IRCCS, Milan, 20145 Italy
• Medicina II Cardiovascolare, AUSL-IRCCS di Reggio Emilia, Reggio Emilia, Italy
• Dipartimento di Scienze Mediche, Chirurgiche e della Salute, Università degli studi di Trieste, Trieste, Italy