Recruiting

Cohort Study on Plant-based Diets (COPLANT Study)

ClinicalTrials.gov IDNCT06323538

PhaseNot Applicable

Enrollment6000

SponsorGerman Federal Institute for Risk Assessment

Age18 Years

SexALL

I'm interested View official listing

Conditions studied

Dietary Exposure, Diabetes Mellitus, Type 2, Cardiovascular Diseases, Bone Loss, Sustainability, Exposure, Obesity, Vitamin Deficiency, Mineral Deficiency

About this study

The Cohort on Plant-based Diets (COPLANT) study is a multi-centre cohort study that starts baseline recruitment from 2024 to 2027 with approximately 6,000 participants in Germany and Austria. The COPLANT study focuses on vegan (no animal products), vegetarian (no meat and fish, but dairy products and eggs), pescetarian (no meat, but fish) and omnivorous (mixed diet including all possible animal products) diets. The aim of the COPLANT study is to gain new insights on health benefits and risks as well as social, ecological and economic effects of different plant-based diets in comparison to a mixed diet. In addition to a detailed dietary survey using an app adapted to the needs of this study, the baseline examination includes measurements of body composition, bone health, cardiovascular risk factors, diabetes risk, contaminants and lifestyle. For the basic laboratory program, fasting blood, 24-hour urine collection and a stool sample are taken from all study participants. Furthermore, specific aspects of dietary behavior, physical activity and other lifestyle factors are collected via questionnaires. Follow-up studies are planned at intervals of 5, 10 and 20 years after the baseline visit.

Primary outcomes

Incidence of diabetes type 2 (5, 10, 20 years)

Eligibility information

Inclusion Criteria: * age between 18 and 69 years at recruitment (age-stratified recruitment in four age groups (18 to 29, 30 to 39, 40 to 49 and 50 to 69 years) which should be equally distributed across the four diets) * following their current diet for at least one year * health insured * are willing to have blood taken (adults) * are willing and able to complete questionnaires * only at Berlin, Jena, Giessen and Karlsruhe sites: pregnant and breastfeeding women were recruited (shortened examination programm) * only at the Regensburg, Heidelberg, Bonn and Vienna sites: are neither pregnant nor breastfeeding at the time of recruitment * only at Berlin and Karlsruhe sites: children of adult participants (shortened examination programm without collection of blood, urine, and stool) * are able to give informed consent to participate in the study * have given their consent to participate in the COPLANT study Exclusion Criteria: * who can no longer be contacted * who withdraw their consent to participate in the study

Study locations

University Vienna, Vienna, 1090 Austria
Max Rubner-Institut, Karlsruhe, Baden-Wurttemberg 76131 Germany
Friedrich-Schiller University, Jena, Thuringia 07743 Germany
The German Federal Institut for Risk Assessment, Berlin, 10589 Germany
University Bonn, Bonn, Germany
Research Institute for Plant-Based Nutrition, Gießen, Giessen, 35444 Germany
University Heidelberg, Heidelberg, 69120 Germany
University Regensburg, Regensburg, 93053 Germany

Before you participate: Varda Clinical is an independent discovery tool, not the study sponsor or a medical provider. Eligibility can only be determined by the official study team. Discuss potential risks and benefits with a qualified healthcare professional.

Source: ClinicalTrials.gov. Record last refreshed by Varda Clinical: 2026-09-27.