Whole Genome Sequencing in Breast Cancer

\[Prospective study\] Inclusion Criteria: * Patients who have consented to both the patient consent form and the consent for the use of human-derived materials. * Patients who are aged 19 years or older at the time of signing the consent form. * Patients capable of providing written consent to participate voluntarily in the study. * Patients eligible for tissue examination and surgical removal to facilitate sample collection. * Patients histologically confirmed with breast cancer or undergoing tissue examination for pathological confirmation due to imaging findings suggestive of breast cancer. Exclusion Criteria: * Patients who do not understand or refuse to consent in writing. * Patients for whom obtaining sufficient samples is challenging. * Patients who refuse genetic testing. \[Retrospective study\] Inclusion Criteria: * Patients histologically confirmed with breast cancer. * Patients for whom breast cancer tissues collected between 2012 and 2023 are stored in the Samsung Seoul Hospital Biobank and available for distribution. Exclusion Criteria: \- Patients for whom sufficient tissue for analysis is not adequately stored.