Recruiting
Computerized Cognitive Behavioral Therapies for Suicide Prevention and Depression
This study plans to learn more about the use of one of two self-guided online cognitive behavioral therapy courses. One is focused on symptoms of depression and one is focused on history of suicidal thoughts and behaviors.
ClinicalTrials.gov IDNCT06375083
PhasePHASE2
Enrollment472
SponsorVA Eastern Colorado Health Care System
Age18 Years – 65 Years
SexALL
Conditions studied
Suicide, Depression
About this study
This study plans to learn more about the use of one of two self-guided online cognitive behavioral therapy courses. One is focused on symptoms of depression and one is focused on history of suicidal thoughts and behaviors.
Interventions
- Behavioral: c-CBT for Suicide Prevention — Online c-CBT for SP The computerized Cognitive Behavioral Therapy for Suicide Prevention (cCBT-SP) course is comprised of 12 online sessions and is augmented by use of a companion workbook.
- Behavioral: c-CBT or Depression — The computerized Cognitive Behavioral Therapy for Depression (cCBT-D) course is comprised of 12 online sessions and is augmented by use of a companion workbook.
Primary outcomes
- Client Satisfaction Questionnaire (12 weeks)
- Internet Evaluation and Utility Questionnaire (12 weeks)
- Internet Impact and Effectiveness Questionnaire (12 weeks)
- Narrative Evaluation of Intervention Interview (12 weeks)
- Recruitment Rate (12 weeks)
- Completion of intervention (12 weeks)
Eligibility information
Cohort A - cCBT-SP Program
Inclusion Criteria:
1. Veterans between the ages of 18 and 65
2. Currently living in Colorado, New York, Montana, Texas, or Utah who have accessed VA Care
3. Recent suicidal ideation (past month; C-SSRS Screener -Yes to Item 2) and history of lifetime suicidal behavior (lifetime, C-SSRS Screener - Yes to Item 6)
4. Reliable access to a computer/tablet and the internet
5. Ability to provide informed consent
Exclusion Criteria:
1. Active alcohol or substance use disorder, excluding Cannabis dependence, as determined by screening or electronic medical record
2. Identification of active psychosis or bipolar disorder, as determined via screening or electronic medical record
3. Severe cognitive impairment, as determined by screening or electronic medical record
4. Currently enrolled in/participating in another mental health-related intervention research study
Cohort B - cCBT-D Program
Inclusion Criteria:
1. Veterans between the ages of 18 and 65
2. Currently living in Colorado, New York, Montana, Texas, or Utah who have accessed VA care
3. Mild to moderate depressive symptoms, as determined by the PHQ-9, (score of 5-14)
4. Reliable access to a computer/tablet and the internet
5. Ability to provide informed consent
Exclusion Criteria:
1. PHQ-9 score below 4 or 15 and above
2. Active alcohol or substance use disorder, excluding Cannabis dependence, as determined by screening or electronic medical record
3. Identification of active psychosis or bipolar disorder, as determined via screening or electronic medical record
4. Severe cognitive impairment, as determined by screening or electronic medical record
5. Currently enrolled in/participating in other intervention research study
Study locations
- Eastern Colorado Health Care System, Aurora, Colorado 80045 United States
Before you participate: Varda Clinical is an independent discovery tool, not the study sponsor or a medical provider. Eligibility can only be determined by the official study team. Discuss potential risks and benefits with a qualified healthcare professional.
Source: ClinicalTrials.gov. Record last refreshed by Varda Clinical: 2026-10-13.