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Intensive Patient Referral and Education Program Prior to Renal Replacement Therapy

Intensive Patient Referral and Education Program prior to Renal Replacement Therapy (iPREP-RRT) is a 12-week intervention that identifies hospitalized African Americans with advanced chronic kidney disease (CKD) and provides them with hospital- and community-based education, navigation and self-management support. Participants will be randomized to the iPREP-RRT intervention versus enhanced usual care.

ClinicalTrials.gov IDNCT06397456
PhaseNA
Enrollment180
SponsorUniversity of Chicago
Age18 Years – 70 Years
SexALL
I'm interested View official listing

Conditions studied

Chronic Kidney Disease, Hypertension

About this study

Intensive Patient Referral and Education Program prior to Renal Replacement Therapy (iPREP-RRT) is a 12-week intervention that identifies hospitalized African Americans with advanced chronic kidney disease (CKD) and provides them with hospital- and community-based education, navigation and self-management support. Participants will be randomized to the iPREP-RRT intervention versus enhanced usual care.

Interventions

Primary outcomes

Eligibility information

Inclusion Criteria: * Patients over the age of 18 and under 70 * Admitted to the University of Chicago inpatient general medicine service * Likely hospital stay greater than 48 hours * Diagnosis of advanced CKD (Stage 3B or above, as determine by problem list, ICD- 10 codes or eGFR\<45 during admission and from previous medical encounters) * Self-identify as Black or African American Exclusion Criteria: * Non-English speaking * Unable to communicate due to current medical status * Unable to consent due to mental status * Expected hospital stay less than 24 hour * Current admission in ICU

Study locations

Before you participate: Varda Clinical is an independent discovery tool, not the study sponsor or a medical provider. Eligibility can only be determined by the official study team. Discuss potential risks and benefits with a qualified healthcare professional.

Source: ClinicalTrials.gov. Record last refreshed by Varda Clinical: 2026-10-21.