Intensive Patient Referral and Education Program Prior to Renal Replacement Therapy
Intensive Patient Referral and Education Program prior to Renal Replacement Therapy (iPREP-RRT) is a 12-week intervention that identifies hospitalized African Americans with advanced chronic kidney disease (CKD) and provides them with hospital- and community-based education, navigation and self-management support. Participants will be randomized to the iPREP-RRT intervention versus enhanced usual care.
Conditions studied
Chronic Kidney Disease, Hypertension
About this study
Intensive Patient Referral and Education Program prior to Renal Replacement Therapy (iPREP-RRT) is a 12-week intervention that identifies hospitalized African Americans with advanced chronic kidney disease (CKD) and provides them with hospital- and community-based education, navigation and self-management support. Participants will be randomized to the iPREP-RRT intervention versus enhanced usual care.
Interventions
- Behavioral: In-Person Patient Education — In-person patient education about CKD, CKD risk factor management and renal replacement therapy options.
- Behavioral: Commitment to Change — Motivational interviewing to assist participants in committing to change in CKD management or RRT selection.
- Behavioral: Blood pressure monitoring — Participants will learn how to check their blood pressure and will receive a blood pressure cuff for home.
- Behavioral: Written Patient Education — Written patient education booklet about general health care management including taking medications, having a primary care doctor, weight management and exercise.
- Behavioral: Text-based reinforcement for CKD self-management — Patient educator will use text messages based on social cognitive theory to remind participants about and reinforce goals set around CKD self-management, blood pressure control and RRT selection
- Behavioral: Community-based education session, reinforcement for self-management — Patient educator will use provide a "booster" session based on social cognitive theory to remind participants about and reinforce goals set around CKD self-management, blood pressure control and RRT selection
- Behavioral: Text-based reinforcement for general health self-management — Patient educator will use text messages to send general health management messages
Primary outcomes
- Kidney Disease Knowledge Questionnaire (KIKS) (Baseline, 1 day Post Brief Intervention, Week 4, Week 12, Week 16)
- ESRD Knowledge (Baseline, 1 day Post Brief Intervention, Week 4, Week 12, Week 16)
- Blood Pressure Knowledge (Baseline, 1 day Post Brief Intervention, Week 4, Week 12, Week 16)
- CKD Self-Management (Baseline, Week 8, Week 12, Week 16)
Eligibility information
Study locations
- University of Chicago Medical Center, Chicago, Illinois 60637 United States
Source: ClinicalTrials.gov. Record last refreshed by Varda Clinical: 2026-10-21.