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Pancreatic Insulin Production Capacity (PIPC) - a Feasibility Study

The standard treatment for Type 2 diabetes involves management of the disease based on average of blood glucose control over the past few months. In this study, the investigators test for the participants' ability to produce insulin, which is the hormone that the body makes to control blood sugar levels. The body produces insulin in response to eating. The participants will drink a meal replacement shake, and then test the blood for levels of insulin produced over 2 hours. With blood tests taken five times over…

ClinicalTrials.gov IDNCT06462170
PhaseNA
Enrollment90
SponsorOttawa Hospital Research Institute
Age18 Years
SexALL
I'm interested View official listing

Conditions studied

Type 2 Diabetes

About this study

The standard treatment for Type 2 diabetes involves management of the disease based on average of blood glucose control over the past few months. In this study, the investigators test for the participants' ability to produce insulin, which is the hormone that the body makes to control blood sugar levels. The body produces insulin in response to eating. The participants will drink a meal replacement shake, and then test the blood for levels of insulin produced over 2 hours. With blood tests taken five times over two hours, the investigators will measure the blood glucose (sugar), and insulin levels. This study will assess the differences in insulin produced in the participants and try to understand the reasons for these differences.

Interventions

Primary outcomes

Eligibility information

Inclusion Criteria: 1. Consent provided 2. Age \>= 18 years. 3. Diagnosed as type 2 diabetes mellitus. 4. Not on insulin therapy. Exclusion Criteria: 1. Diagnosed as another form of diabetes mellitus. 2. Allergic to one or more ingredients in Boost meal replacement shake. 3. Unable to fast since midnight and attend in person for the morning protocol.

Study locations

Before you participate: Varda Clinical is an independent discovery tool, not the study sponsor or a medical provider. Eligibility can only be determined by the official study team. Discuss potential risks and benefits with a qualified healthcare professional.

Source: ClinicalTrials.gov. Record last refreshed by Varda Clinical: 2026-09-27.