Recruiting
Cognitive Enhancement in Unipolar Depression With Yoga
It is evident from recent studies that cognitive deficits persist even after remission of depressive episode. Hence, in this study, the investigators would like to see whether specific Yoga practice will help in enhancing cognitive abilities in this population.
ClinicalTrials.gov IDNCT06472492
PhaseNA
Enrollment32
SponsorUniversity of Pittsburgh
Age18 Years
SexALL
Conditions studied
Unipolar Depression
About this study
It is evident from recent studies that cognitive deficits persist even after remission of depressive episode. Hence, in this study, the investigators would like to see whether specific Yoga practice will help in enhancing cognitive abilities in this population.
Interventions
- Behavioral: Adjuvant yoga intervention — The yoga will include following asanas under the supervision of a yoga therapist. This will include Griva Shithilikarana, Skandha Sanchalana , Kati Sanchalana, Jaanu Sanchalana, Pada Sanchalana, Tadasana, Kati Sakti Vikasaka, Konasana,Marjari Asana, Vakrasana, Pascimottanasana, Matsyasana, Bhujangasana, Ardha Shalabhasana, Viparitakarani, Pavanamuktasana, Setubhandasana, Shavasana, Kapalabhati, Surya-anuloma pranayama, Chandraanuloma pranayama, Bhastrika, Bhramari Pranayama, Nadanusandhana.
Primary outcomes
- Working memory (Digit Span) (Baseline, after six weeks yoga and after four weeks of completion of yoga)
- Attention and processing speed(Trail A and B) (Baseline, after six weeks yoga and after four weeks of completion of yoga)
- Cognitive flexibility (Baseline,after six weeks yoga and after four weeks of completion of yoga)
- Cognitive inhibition (Baseline,after six weeks yoga and after four weeks of completion of yoga)
Eligibility information
Inclusion Criteria:
* Age more than 18years and less than 60 years
* H/o at least one depressive episode which is under remission and at the time of examination and throughout the study duration,
* Informed Consent
Exclusion Criteria:
* Comorbid Psychosis, OCD, Bipolar disorder
* Comorbid ADHD, IDD
* Comorbid substance dependence (except tobacco)
* Comorbid major or minor cognitive impairment,
* Bi temporal ECT within 6 months
* Past yoga practice - regularly for 1 month within 3 months Pregnancy
Study locations
- National Institute of Mental Health and Neuroscience (NIMHANS), Bengaluru, Karnataka 560029 India
Before you participate: Varda Clinical is an independent discovery tool, not the study sponsor or a medical provider. Eligibility can only be determined by the official study team. Discuss potential risks and benefits with a qualified healthcare professional.
Source: ClinicalTrials.gov. Record last refreshed by Varda Clinical: 2026-09-27.