Non-invasive Tools for PSVD Diagnosis
Patients treated with platinum-based chemotherapy drugs have the probability of developing PSVD. The diagnosis of PSVD depends on liver biopsy. In addition, the level of portal vein pressure has guiding value in the diagnosis and prognosis of PSVD. Many studies have shown that liver and spleen stiffness have high accuracy in diagnosis and prognosis. The purpose of this study is to evaluate the efficacy of the combination of liver and spleen stiffness in the diagnosis of PSVD and to search for effective biomarkers…
Conditions studied
Non-Cirrhotic Portal Hypertension, Porto-Sinusoidal Vascular Diseases
About this study
Patients treated with platinum-based chemotherapy drugs have the probability of developing PSVD. The diagnosis of PSVD depends on liver biopsy. In addition, the level of portal vein pressure has guiding value in the diagnosis and prognosis of PSVD. Many studies have shown that liver and spleen stiffness have high accuracy in diagnosis and prognosis. The purpose of this study is to evaluate the efficacy of the combination of liver and spleen stiffness in the diagnosis of PSVD and to search for effective biomarkers for the diagnosis of PSVD through a single-center, prospective, observational study.
Interventions
- Diagnostic Test: liver and stiffness measurement — liver and spleen stiffness measurement are non-invasive tools for evaluation of cirrhosis and portal hypertension
Primary outcomes
- Searching for valid non-invasive tools for the diagnosis of PSVD (2 years)
Eligibility information
Study locations
- Nanfang hospital, Southern Medical Uiversity, Guangzhou, Guangdong 510080 China
Source: ClinicalTrials.gov. Record last refreshed by Varda Clinical: 2026-09-27.