Preoperative vs. Pathologic Size in Breast Cancer: A Prospective Study
Breast cancer, the most prevalent malignancy among women globally, is increasing in incidence. While non-metastatic breast cancer requires surgery, determining the optimal extent of resection remains challenging. Inadequate resection margins necessitate reoperation, leading to increased psychological stress, costs, and potentially compromised cosmetic outcomes and prognosis. Accurate preoperative assessment of resection extent is crucial and involves various factors, including imaging studies, physical…
Conditions studied
Mastectomy, Breast Neoplasm Malignant Primary
About this study
Breast cancer, the most prevalent malignancy among women globally, is increasing in incidence. While non-metastatic breast cancer requires surgery, determining the optimal extent of resection remains challenging. Inadequate resection margins necessitate reoperation, leading to increased psychological stress, costs, and potentially compromised cosmetic outcomes and prognosis. Accurate preoperative assessment of resection extent is crucial and involves various factors, including imaging studies, physical examinations, tumor molecular subtypes, and intraductal carcinoma components. This prospective observational study aims to identify and integrate multiple predictive factors to enhance surgical planning and minimize reoperation rates in breast cancer patients.
Interventions
- Other: No additional intervention — All patients are scheduled to undergo standard breast surgery as part of their routine clinical care. No additional interventions are administered specifically for this study.
Primary outcomes
- Concordance rate by the intraclass correlation coefficient Factors associated with discrepancies (Within 30 days after surgery)
Eligibility information
Study locations
- Incheon St. Mary's Hospital, Incheon, South Korea
Source: ClinicalTrials.gov. Record last refreshed by Varda Clinical: 2026-09-27.