Recruiting
Non-Invasive Measurements of Changes in Pulmonary Artery Pressure in Intensive Care Unit Patients Using Electrical Impedance Tomography - A Feasibility Study
To assess whether changes in electrical impedance - measured using an electrical impedance tomography (EIT) chest belt - can be used to derive changes in pulmonary artery pressure (PAP) in critically ill patients when compared to invasive gold-standard PAP measured using pulmonary artery catheter (PAC).
ClinicalTrials.gov IDNCT06544148
PhaseNot Applicable
Enrollment28
SponsorInsel Gruppe AG, University Hospital Bern
Age18 Years
SexALL
Conditions studied
Pulmonary Artery Hypertension
About this study
To assess whether changes in electrical impedance - measured using an electrical impedance tomography (EIT) chest belt - can be used to derive changes in pulmonary artery pressure (PAP) in critically ill patients when compared to invasive gold-standard PAP measured using pulmonary artery catheter (PAC).
Interventions
- Device: Electrical impedance tomography — In addition to routine critical care with a pulmonary artery catheter already in place (PAC), an electrical impedance tomography (EIT) belt will be placed in patients enrolled in this study. Data will be analyzed offline and clinical trajectory and/or decisions will not be impacted by this additional monitoring. EIT is a non-invasive, safe, and radiation-free medical imaging modality.
Primary outcomes
- Mean difference between EIT-derived and PAC-measured changes in pulmonary artery pressure (Up to 48 hours)
Eligibility information
Inclusion criteria:
* Age ≥ 18-year-old.
* Intubated patients in the ICU with clinical decision to monitor PAP and cardiac output using a PAC.
Exclusion criteria:
* Patients with implanted or external thoracic electronic devices (e.g., pacemaker) or thoracic metal implants.
* Known pregnancy or lactating patients.
* Open lung injuries or pneumothorax.
* Open wounds, drainages, burns or rashes of the upper thorax.
* Estimated thoracic perimeter smaller than 66 cm or larger than 134 cm.
* Known allergies to wound dressings or adhesives (e.g., gel electrodes)
Study locations
- Inselspital Bern, Universitätsklinik für Intensivmedizin, Bern, 3010 Switzerland
Before you participate: Varda Clinical is an independent discovery tool, not the study sponsor or a medical provider. Eligibility can only be determined by the official study team. Discuss potential risks and benefits with a qualified healthcare professional.
Source: ClinicalTrials.gov. Record last refreshed by Varda Clinical: 2026-09-27.