Balance Control and Recovery in Diabetes Peripheral Neuropathy

Conditions studied

Diabetic Peripheral Neuropathy, Diabetic Peripheral Neuropathy Type 2, Diabetic Peripheral Neuropathy Type 2 - Uncontrolled, Healthy Aging

About this study

In this study the effects of diabetic peripheral neuropathy will be assessed on balance control, balance recovery, and muscle electrical activity in adults over 50 years. Aim 1: Determine muscle activity and balance control during a sit-to-stand in adults age above 50 with and without diabetic peripheral neuropathy. Aim 2: Assess local balance recovery and latency responses to lateral surface perturbation during quiet standing.

Interventions

• Behavioral: sit-to-stand — test for balance during movement from sitting to standing
• Behavioral: stand to sit — test for balance during movement from standing to sitting
• Behavioral: standing perturbation — test for balance recovery following perturbation
• Other: MRI of sciatic nerve — measure of peripheral nerve diameter

Primary outcomes

• Center of pressure using force plate (First session (immediately after intervention))
• Center of mass using Vicon cameras. (First session (immediately after intervention))
• Joint moment using Nexus software (First session (immediately after intervention))
• Local dynamic stability using Motek and Vicon system (First session (immediately after intervention))

Eligibility information

Study locations

• The University of Texas at Austin, Austin, Texas 78712 United States