Recruiting

Psychiatric Multi-omics and Neuroimaging Project

This study focuses on the structure and function of the brain and gene expression in peripheral blood of patients with schizophrenia, to explore the interaction and influence between the three. Patients with mental disorders who have been recruited will take their medication regularly for 1 year and participate in baseline and follow-up assessments.

ClinicalTrials.gov IDNCT06580860

PhaseNot Applicable

Enrollment1899

Sponsormingjun Zhong

Age13 Years

SexALL

I'm interested View official listing

Conditions studied

Mental Disorders, Healthy Control

About this study

Interventions

Drug: Antipsychotic drugs, antidepressants, mood stabilizers, and sleep aids — Patients with mental disorders should take the appropriate medicine as prescribed by the doctor，and the health norms are not required to take medicine.This study will not interfere with the medication regimen of doctors.

Primary outcomes

cortical morphology (40 minutes)
target gene charaacteristics (1 day)
scale scores (90 minutes.)

Eligibility information

Inclusion Criteria: * Age: 13-35 years old(Patients with healthy siblings can be extended to 14-35 years of age) * Course of disease: \<24 months * Priority is given to patients who have never taken medicine or duration of drug use \< 2 weeks * No nuclear magnetic contraindications. Exclusion Criteria: * Family history of psychotic disorders, history of psychoactive substances abuse, alcohol dependence, or nicotine dependence * Have a major physical disease or infectious disease * History of coma and serious neurological disease 4.MRI contraindications.

Study locations

The Second Xiangya hospital of central south univerity, Changsha, Hunan 410000 China

Before you participate: Varda Clinical is an independent discovery tool, not the study sponsor or a medical provider. Eligibility can only be determined by the official study team. Discuss potential risks and benefits with a qualified healthcare professional.

Source: ClinicalTrials.gov. Record last refreshed by Varda Clinical: 2026-09-27.