Recruiting

SER Familia: A Family-Based Intervention Addressing Syndemic Conditions Among Latino Immigrant Families

ClinicalTrials.gov IDNCT06627764

PhaseNA

Enrollment400

SponsorDuke University

Age12 Years

SexALL

I'm interested View official listing

Conditions studied

Substance Abuse, Intimate Partner Violence (IPV), HIV Infections, Depression, Anxiety

About this study

This study aims to prevent syndemic health conditions by decreasing acculturative stress and promoting resilience via SER Familia (Salud, Estrés y Resilencia en Familias/ Health, Stress, and Resilience in Families), a family-based intervention. SER Familia is a six-session intervention co-developed and delivered by community health workers (CHWs) that uses strategies to reduce acculturative stress, promote resilience, improve parent-child and family level health, while simultaneously helping families maintain strong social networks and better navigate community resources to address social determinants of health (SDOH). More specifically, investigators aim to: 1) Examine the efficacy of SER Familia to prevent or reduce the syndemic comprised of substance abuse, IPV, HIV risk, depression, and anxiety among Parents and Youth; and 2) Identify how individual, family, and community mechanisms of change related to acculturative stress and resilience mediates the effect of SER Familia.

Interventions

Behavioral: SER Familia — SER Familia is a six-session intervention co-developed and delivered by community health workers (CHWs) that uses strategies to reduce acculturative stress, promote resilience, improve parent-child and family level health, while simultaneously helping families maintain strong social networks and better navigate community resources to address social determinants of health (SDOH).

Primary outcomes

Change in Parent Acculturative stress as measured by the Hispanic Stress Inventory (HSI-2) Immigrant Version (From Enrollment to end of treatment at 6 weeks)
Change in Youth Acculturative stress as measured by the Hispanic Stress Inventory - Adolescent (HSI-A) (From Enrollment to end of treatment at 6 weeks)
Change in individual resilience as measured by the 25-item Resiliency Scale (From Enrollment to end of treatment at 6 weeks)
Change in PROMIS (Patient-Reported Outcomes Measurement Information System) Global Health (From Enrollment to end of treatment at 6 weeks)

Eligibility information

Inclusion Criteria: * Eligible participants must identify as Hispanic/Latino/a/x/e, * be a first generation immigrant parent or parental figure (Parent) * have a child (Youth) aged 12-17 * speak English and/or Spanish Exclusion Criteria: * Families planning to move within two years will be excluded

Study locations

Duke School of Nursing, Durham, North Carolina 27707 United States

Before you participate: Varda Clinical is an independent discovery tool, not the study sponsor or a medical provider. Eligibility can only be determined by the official study team. Discuss potential risks and benefits with a qualified healthcare professional.

Source: ClinicalTrials.gov. Record last refreshed by Varda Clinical: 2026-09-27.