Recruiting
Meditative Neurofeedback for Depression
The goal of this study is to test a meditative neurofeedback intervention for depressed mood.
ClinicalTrials.gov IDNCT06675240
PhasePHASE1
Enrollment60
SponsorUniversity of California, San Diego
Age18 Years and older
SexALL
Conditions studied
Depression - Major Depressive Disorder, Depression Disorders
About this study
The goal of this study is to test a meditative neurofeedback intervention for depressed mood.
Interventions
- Behavioral: MediNF — Over 5-sessions participants will engage in a breath-focused meditative practice with frontal brain connectivity neurofeedback provided to enhance performance.
- Behavioral: ShamMediNF — Over 5-sessions participants will engage in a breath-focused meditative practice with frontal brain connectivity neurofeedback provided that is yoked to a closely-matched individual in the experimental arm.
Primary outcomes
- Change in FCz-FC4 alpha band coherence (iCoh) (8 weeks)
Eligibility information
Inclusion Criteria:
* moderate depression per PHQ9 symptom ratings
Exclusion Criteria:
* active substance abuse/dependence
* psychotic disorders
* bipolar disorder
* displaying acutely suicidal behaviors
Study locations
- University of California San Diego, La Jolla, California 92093 United States
Before you participate: Varda Clinical is an independent discovery tool, not the study sponsor or a medical provider. Eligibility can only be determined by the official study team. Discuss potential risks and benefits with a qualified healthcare professional.
Source: ClinicalTrials.gov. Record last refreshed by Varda Clinical: 2026-10-27.