Osaka Cardiometabolic Epidemiological Study: Ohtori Study Part 2

Conditions studied

Type 2 Diabetes Mellitus (T2DM), Type 2 Diabetes, Diabetes Mellitus, Hypertension, Hyperglycemia, Hyperlipidemia, Dyslipidemia, Hyperuricemia or Gout, Hyperuricemia, Gout, Obesity, Obesity/Epidemiology, Obesity, Abdominal, Central Obesity, Visceral Fat, Chronic Kidney Disease(CKD), Atherosclerosis, Metabolic Syndrome, Hepatic Steatosis, Insulin Sensitivity/Resistance

About this study

The aim of this study is to investigate the relationship between body fat distribution measured by CT scan and related risk factors with the risk of incident metabolic and cardiovascular disease in a prospective cohort study of Japanese men and women. The investigators will also investigate novel risk factors for metabolic and cardiovascular disease using molecular weight-based metallomics analysis.

Primary outcomes

• Type 2 diabetes is diagnosed based on the results of a fasting blood glucose test and medication history. (Investigators plan to conduct follow-up examinations at intervals of one to two years.)
• Hypertension is diagnosed based on the results of blood pressure measurement and medication history. (Investigators plan to conduct follow-up examinations at intervals of one to two years. plan to conduct follow-up examinations at intervals of one to two years.)
• Dyslipidemia is diagnosed based on the National Cholesterol Education Program (NCEP) Adult Treatment Panel III guidelines. (Investigators plan to conduct follow-up examinations at intervals of one to two years. plan to conduct follow-up examinations at intervals of one to two years.)
• Metabolic syndrome is diagnosed based on the Joint Interim Statement published in Circulation. 2009 Oct 20;120(16):1640-5. (Investigators plan to conduct follow-up examinations at intervals of one to two years. plan to conduct follow-up examinations at intervals of one to two years.)
• Hyperuricemia is defined based on fasting serum uric acid levels and the use of oral medication. (Investigators plan to conduct follow-up examinations at intervals of one to two years. plan to conduct follow-up examinations at intervals of one to two years.)
• Low eGFR was define based on the Modification of Diet in Renal Disease study equation for Japanese. (Investigators plan to conduct follow-up examinations at intervals of one to two years. plan to conduct follow-up examinations at intervals of one to two years.)

Eligibility information

Study locations

• The Ohtori Health Promotion Center, Sakai, Osaka 5938324 Japan