Transdiagnostic Internet-delivered Intervention for Adolescents With Anxiety and Depression
The goal of this clinical trial is to test the efficacy of a transdiagnostic Internet-delivered interventions for Romanian adolescents with anxiety and/ or depression. The main questions it aims to answer are: * What is the clinical efficacy of the Internet-delivered intervention? * How accurate is the prediction model in predicting who will respond to treatment? Participants will undergo non-invasive fMRI to measure variability in brain signal as a proxy of the neural systems' adaptability before receiving the…
Conditions studied
Anxiety Disorders, Depressive Disorder, Social Anxiety Disorder, Major Depressive Disorder, Dysthymia, Generalized Anxiety Disorder
About this study
The goal of this clinical trial is to test the efficacy of a transdiagnostic Internet-delivered interventions for Romanian adolescents with anxiety and/ or depression. The main questions it aims to answer are: * What is the clinical efficacy of the Internet-delivered intervention? * How accurate is the prediction model in predicting who will respond to treatment? Participants will undergo non-invasive fMRI to measure variability in brain signal as a proxy of the neural systems' adaptability before receiving the intervention, then they will be allocated either to the Internet-delivered intervention or control group.
Interventions
- Behavioral: Transdiagnostic Internet-delivered intervention — The intervention consists of 8 modules based on Rational emotive therapy, delivered via 8 weeks.
Primary outcomes
- Internalizing problems (baseline, after 8 weeks of intervention, 6 months follow-up)
Eligibility information
Study locations
- Babes-Bolyai University, Cluj-Napoca, 400015 Romania
- Babeș-Bolyai University, Cluj-Napoca, 400015 Romania
Source: ClinicalTrials.gov. Record last refreshed by Varda Clinical: 2026-09-27.