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Acupoint Selection Based on Meridian Theory in Primary Insomnia of Liver Depression and Spleen Deficiency Type

ClinicalTrials.gov IDNCT06782815

PhaseNA

Enrollment96

SponsorChuanlong Zhou

Age18 Years

SexALL

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Conditions studied

Primary Insomnia

About this study

The classical literature combined with modern medicine to select acupoints, in order to intervene in the autonomic nerve function of the superior cervical sympathetic ganglion as an opportunity, put forward the meridian acupoints mainly to reconcile the head orifices Ying Wei, acupuncture treatment of primary insomnia clinical research. Heart rate variability ( HRV ), Pittsburgh sleep quality index ( PSQI ), polysomnography ( PSG ) and the MOS item short from health survey ( SF-36 ) were observed. Insomnia Severity Index ( ISI ), Dysfunctional Beliefs and Attitudes about Sleep Scale 16 ( DBAS-16 ), GABA, Glx and other secondary indicators were used to clarify the clinical short-term and long-term efficacy of different acupoints in the treatment of patients with primary insomnia and the intervention effect on HRV.

Interventions

Device: Acupuncture — acupuncture Baihui, Sishencong ; acupuncture bilateral Qimen, Zhangmen, Hegu, Taichong, reinforcing and reducing, until the acid swelling is obvious,stopped ferforming acupuncture, the needle was retained for 30 min.
Device: Acupuncture — （1）Acupuncture bilateral Tianrong points, obliquely 45 ± 5 ° backward, 1-1.5 inch deep, reinforcing and reducing horizontally, and stop the needle when the auricle has a heat sensation ; （2）Acupuncture at bilateral Tianyou points, pointing to the tip of the nose, with a depth of 0.5-1 inches, flat reinforcing and reducing, until the sense of soreness and distension obviously stops, and the needle is retained for 30 minutes.

Primary outcomes

Sleep quality measured by Pittsburgh sleep quality index ( PSQI) (Before treatment, 4 weeks of treatment, and 4 weeks after the end of treatment, three time points were observed.)
Quality of life measure by 36-item short form health survey（SF-36） (Before treatment, 4 weeks of treatment, and 4 weeks after the end of treatment, three time points were observed.)

Eligibility information

Inclusion Criteria: * In line with the diagnostic criteria of insomnia of liver depression and spleen deficiency type in traditional Chinese medicine : * In line with the Western diagnostic criteria for insomnia ; * 18 ≤ age ≤ 40 years old, male or female ; * patients with a course of more than two weeks ; Note: The above criteria must be met for inclusion in this study. Exclusion Criteria: * Insomnia caused by a variety of organic diseases, neurological or psychiatric disorders * Pregnancy, lactation or drug allergy * There are more serious primary diseases such as cardiovascular and cerebrovascular diseases, gastrointestinal diseases, endocrine system diseases, or psychiatric patients. * Patients with coagulation dysfunction and bleeding tendency.

Study locations

The Third Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, Zhejiang 321000 China

Before you participate: Varda Clinical is an independent discovery tool, not the study sponsor or a medical provider. Eligibility can only be determined by the official study team. Discuss potential risks and benefits with a qualified healthcare professional.

Source: ClinicalTrials.gov. Record last refreshed by Varda Clinical: 2026-09-27.