Recruiting

Association Between Genetic Polymorphisms and Type 2 Asthma in Children

To further understand the role of gene single nucleotide polymorphism (SNP) in the occurrence of type 2 inflammation-related asthma in children by analyzing the gene single nucleotide polymorphism (SNP), lung function and type 2 inflammation indicators of children diagnosed with asthma in outpatient and inpatient. To provide a theoretical basis for the study of personalized treatment and prevention strategies for asthma.

ClinicalTrials.gov IDNCT06840717

PhaseNot Applicable

Enrollment300

SponsorGuangzhou Institute of Respiratory Disease

Age3 Years

SexALL

I'm interested View official listing

Conditions studied

Asthma in Children, Genetic Disease, Inflammation

About this study

Primary outcomes

type 2 inflammation indicators (Outpatient visits for the first time)
pulmonary function indicators (Outpatient visits for the first time)
single nucleotide polymorphism (Outpatient visits for the first time)

Eligibility information

Inclusion Criteria: 1. All children with asthma diagnosis accord with the GINA in 2023 edition; 2. Other diseases that could cause wheezing and cough were excluded, such as acute laryngitis, diphtheria, congenital airway abnormalities, and tracheal foreign bodies; 3. In front of the hospital 2 weeks without antibiotics, systemic hormone medication history; 4. There were no other complications, such as congenital heart disease, pneumonia, gastroesophageal reflux disease, muscle dysplasia, etc. Exclusion Criteria: 1. Children who had taken immunosuppressants, antibiotics and other drugs for a long time before admission; 2. Children with primary immunodeficiency disease; 3. The children and their families failed to cooperate or refused the experimental observation.

Study locations

Guangzhou institute of respiratory disease, Guangzhou, Guangdong 510120 China

Before you participate: Varda Clinical is an independent discovery tool, not the study sponsor or a medical provider. Eligibility can only be determined by the official study team. Discuss potential risks and benefits with a qualified healthcare professional.

Source: ClinicalTrials.gov. Record last refreshed by Varda Clinical: 2026-10-01.