Efficacy and Safety of Gonioscopy Assisted Transluminal Trabeculotomy in Patients with Primary Open-angle Glaucoma and Cataract.
Prospective, randomized, , double-blind, clinical trial, comparing the variation of intraocular pressure (IOP) of patients with mild or moderate primary open-angle glaucoma (OAG) and cataract divided into three groups. All study participants should be treated for the pathology with one or more hypotensive medications or, regardless of the number of drugs, when IOP is greater than 20 mmHg and less than 26 mmHg. The two-year follow-up should also compare the reduction in the number of medications used, reoperation…
Conditions studied
Open Angle Glaucoma (OAG)
About this study
Prospective, randomized, , double-blind, clinical trial, comparing the variation of intraocular pressure (IOP) of patients with mild or moderate primary open-angle glaucoma (OAG) and cataract divided into three groups. All study participants should be treated for the pathology with one or more hypotensive medications or, regardless of the number of drugs, when IOP is greater than 20 mmHg and less than 26 mmHg. The two-year follow-up should also compare the reduction in the number of medications used, reoperation rate, adverse effects, visual acuity, endothelial loss, induction of astigmatism, variation in IOP according to axial diameter of the eye, anterior chamber and age, in addition to the existence of change in the quality of life of patients in the postoperative period
Interventions
- Procedure: 360º goniotomy assisted transluminal trabeculotomy — Open the Schlemm Canal for 360º with a polipropilen 5-0 suture via trabecular meshwork.
- Procedure: Phacoemulsification — Cataract Surgery
- Procedure: 180º gonioscopy assisted transluminal trabeculotomy — Open the Schlemm Canal for 180º with a polipropilen 5-0 suture via trabecular meshwork.
Primary outcomes
- Change in intraocular pressure (IOP) after surgery. (From glaucoma medications washout to 2 years after the surgery)
- Change in the number of glaucoma medications after surgery. (From glaucoma medications washout to 2 years after the surgery)
Eligibility information
Study locations
- Instituto de Olhos Ciências Médicas - Faculdade de Ciências Médicas de Minas Gerais, Belo Horizonte, Minas Gerais 30150270 Brazil
Source: ClinicalTrials.gov. Record last refreshed by Varda Clinical: 2026-09-27.