Recruiting

Improving Hypertension Control in Safety-Net Settings: The Boston Hypertension Equity Alliance in Treatment

ClinicalTrials.gov IDNCT06948838

PhaseNA

Enrollment16895

SponsorBoston Medical Center

Age18 Years

SexALL

I'm interested View official listing

Conditions studied

Hypertension, Hypertension Complicated

About this study

High blood pressure (BP) or hypertension (HTN) affects over 100 million individuals in the US, increasing the risk of adverse outcomes, including stroke, myocardial infarction (MI), and chronic kidney disease (CKD). Effective therapies include non-pharmacologic approaches and multiple medication classes. Successful HTN management requires ongoing patient engagement for BP monitoring and treatment intensification. Reaching this goal is challenging, and many patients with HTN do not have controlled BP. Using a collaborative partnership between patients, clinicians, health system and public health stakeholders, and the research team the investigators plan to overcome barriers to widespread implementation of evidence-based health system strategies to improve BP control in a large, urban, primary care-based safety-net setting for diverse populations experiencing disparities in HTN-related outcomes.

Interventions

Behavioral: RBPM — Standardized blood pressure measurement and treatment protocols in clinical practice.
Other: MII — Team-based interventions including multiple evidence-proven interventions such as clinician decision support, monitoring medication non-adherence, use of combination pills, and formulary modifications.

Primary outcomes

Systolic blood pressure (SBP) improvement (Baseline, every 3 months up to 54 months)
Interventions received (Baseline, 54 months)
Patient activation (Baseline, 18 months, 30 months, 36 months, 42 months, 54 months)

Eligibility information

Inclusion Criteria: * Adult (age\>18) patients receiving primary care at one of the 9 participating sites, with primary care provider (PCP) visit in the preceding year * Presence of HTN defined by one or more of: 1) diagnosis included on active problem list, 2) active HTN medications in prior year, 3) 3 separate elevated BP measurements * Uncontrolled HTN defined as systolic blood pressure (SBP)\>140 Exclusion Criteria: * Not meeting the inclusion criteria

Study locations

Boston Healthcare for the Homeless (BHCHP), Boston, Massachusetts 02118 United States
Boston Medical Center Family Medicine, Boston, Massachusetts 02118 United States
Boston Medical Center, General Internal Medicine primary care, Boston, Massachusetts 02118 United States
Neighborhood Health, Boston, Massachusetts 02118 United States
Mattapan Community Health Center, Boston, Massachusetts 02126 United States
Manet Community Health Center, Quincy, Massachusetts 02169 United States
Greater Roslindale Medical and Dental Center (GRMDC), Roslindale, Massachusetts 02131 United States

Before you participate: Varda Clinical is an independent discovery tool, not the study sponsor or a medical provider. Eligibility can only be determined by the official study team. Discuss potential risks and benefits with a qualified healthcare professional.

Source: ClinicalTrials.gov. Record last refreshed by Varda Clinical: 2026-09-28.