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Perinatal Thymic DYsregulation: Characterization of Perinatal Mood Episodes

The perinatal period is recognized as a time of heightened psychological vulnerability. This research aims to improve the diagnosis and therapeutic management of mood episodes occurring during this time. It is integrated into routine clinical care and seeks to standardize the evaluation of criteria used to characterize mood episodes, while also exploring relevant contextual factors. Traditionally, clinical attention has focused on postnatal depression; however, increasing evidence highlights the presence of…

ClinicalTrials.gov IDNCT07008183
PhaseNA
Enrollment200
SponsorCentre Hospitalier Charles Perrens, Bordeaux
Age18 Years
SexFEMALE
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Conditions studied

Perinatal Mental Health

About this study

The perinatal period is recognized as a time of heightened psychological vulnerability. This research aims to improve the diagnosis and therapeutic management of mood episodes occurring during this time. It is integrated into routine clinical care and seeks to standardize the evaluation of criteria used to characterize mood episodes, while also exploring relevant contextual factors. Traditionally, clinical attention has focused on postnatal depression; however, increasing evidence highlights the presence of hypomanic symptoms-such as distractibility, reduced need for sleep, tachypsychia, and irritability-during the postpartum period. These symptoms may coexist with depressive features, resulting in complex clinical presentations that are often difficult to recognize and manage. Consequently, many cases go undiagnosed and untreated. Current research has largely concentrated on depressive episodes (perinatal depression), with less emphasis on manic, hypomanic, or mixed episodes indicative of bipolar disorder. A systematic evaluation of hypomanic symptoms occurring alongside depressive symptoms in the postpartum period could refine clinical diagnosis and support more targeted and effective therapeutic interventions.

Interventions

Primary outcomes

Eligibility information

Inclusion Criteria: * Women over 18 years old * Pregnant or having given birth less than a year ago * First psychiatric consultation for the pregnancy concerned. * Good command of the French language. * Participant affiliated to the social security system * Participant who has given her consent to take part in the study. Exclusion Criteria: * Women who gave birth more than a year ago. * Participant under psychiatric care * Participant under court protection

Study locations

Before you participate: Varda Clinical is an independent discovery tool, not the study sponsor or a medical provider. Eligibility can only be determined by the official study team. Discuss potential risks and benefits with a qualified healthcare professional.

Source: ClinicalTrials.gov. Record last refreshed by Varda Clinical: 2026-09-27.