Hyperspectral Imaging for Prediction of Preeclampsia

Conditions studied

Preeclampsia (PE) Risk, Preeclampsia

About this study

Preeclampsia is a hypertensive pregnancy disorder that can quickly lead to serious, potentially life-threatening outcomes for both the mother and the fetus. Typical features of preeclampsia are by endothelial and microvascular dysfunctionsNotably, such impairments in endothelial function may precede preeclampsia diagnosis and canpersist for years postpartum. In clinical practice, however, no predictive methods have yet been established that specifically reflect endothelial dysfunction in the context of preeclampsia. Hyperspectral imaging represents a new and non-invasive imaging modality that allows contact-free visualization of peripheral microcirculatory dynamics and tissue perfusion. Despite its growing use in other medical fields, this technology has not yet been systematically studied to determine its predictive potential in preeclampsia. The HIPPA project (Systematic Evaluation of Hyperspectral Analysis for Prediction of Preeclampsia) is a prospective observational study to evaluate the applicability of hyperspectral imaging as a new tool for prediction of preeclampsia.

Primary outcomes

• Number of patients with Preeclampsia (up to one week after delivery)
• Risk ratio of the preeclampsia screening (baseline)

Eligibility information

Study locations

• Heidelberg University Hospital, Department of Gynecology and Obstetrics, Heidelberg, 69120 Germany