Recruiting
Breast Cancer BRAs Study (Breast Cancer Biomechanics of Radiotherapy And Surgery)
This study, delivered by Portsmouth Hospitals University NHS Trust in conjunction with the Research Group in Breast Health at the University of Portsmouth \[1\], aims to assess whether it is possible to test breast biomechanics in women who have had surgery with or without radiotherapy for the treatment of breast cancer.
ClinicalTrials.gov IDNCT07135960
PhaseNot Applicable
Enrollment45
SponsorPortsmouth Hospitals NHS Trust
Age18 Years
SexFEMALE
Conditions studied
Breast Cancer Patients
About this study
This study, delivered by Portsmouth Hospitals University NHS Trust in conjunction with the Research Group in Breast Health at the University of Portsmouth \[1\], aims to assess whether it is possible to test breast biomechanics in women who have had surgery with or without radiotherapy for the treatment of breast cancer.
Primary outcomes
- To determine the feasibility of recruitment to a breast biomechanics study in women treated for early breast cancer with surgery +/- adjuvant radiotherapy. (From enrollment to the end of study [through study completion, an average of 1 year])
Eligibility information
Inclusion Criteria:
* Female
* 18 years of age or above
* Early or locally advanced breast cancer classified as B5a or B5b (radical treatment intent)
* Unilateral breast cancer (contralateral breast used as control)
* Receiving or has received breast cancer surgery
* +/- Adjuvant radiotherapy
* Able to travel to the University of Portsmouth Breast biomechanics laboratory
* Participant has capacity to consent.
Exclusion Criteria:
* Metastatic breast cancer diagnosis
* \< 2 weeks post-operative
* \< 4 weeks post-radiotherapy
* Active post-operative breast infection
* Requirement of ongoing breast dressings
* Previous breast surgery to contralateral breast
* Bilateral breast cancer
* Epilepsy (due to strobe on 3D scanner)
* Pregnancy or \<6 weeks post-partum
* Breastfeeding
* Rockwood Frailty score \>5 (or those unable to ambulate un-aided)
* Requiring interpreter.
Study locations
- Queen Alexandra Hospital, Portsmouth, PO6 3LY United Kingdom
Before you participate: Varda Clinical is an independent discovery tool, not the study sponsor or a medical provider. Eligibility can only be determined by the official study team. Discuss potential risks and benefits with a qualified healthcare professional.
Source: ClinicalTrials.gov. Record last refreshed by Varda Clinical: 2026-09-27.